{"title":"Development and Evaluation of Poly(Lactic-Co-Glycolic Acid) Encapsulated Betulinic Acid Nanocarrier for Improved Anti-Tumor Efficacy","authors":"Cyril Tlou Selepe, Khanyisile Sheer Dhlamini, Lesego Tshweu, Lusisizwe Kwezi, Bathabile Ramalapa, Suprakas Sinha Ray","doi":"10.1002/mame.202570004","DOIUrl":null,"url":null,"abstract":"<p><b>Front Cover</b>: Natural anti-tumor agents are highly regarded for their low cytotoxicity towards healthy cells. However, their relatively short systematic half-life and low bioavailability impose hurdles for clinical application. This study introduces a strategy to surmount these obstacles by developing a drug delivery system employing biopolymeric emulsion techniques to optimize the therapeutic efficacy of a natural anti-tumor agent, betulinic acid. More details can be found in article 2400283 by Bathabile Ramalapa, Suprakas Sinha Ray, and co-workers. Suprakas Sinha Ray designed the cover art in collaboration with the team at INMYWORK Studio. \n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 2","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202570004","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Macromolecular Materials and Engineering","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/mame.202570004","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
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Abstract
Front Cover: Natural anti-tumor agents are highly regarded for their low cytotoxicity towards healthy cells. However, their relatively short systematic half-life and low bioavailability impose hurdles for clinical application. This study introduces a strategy to surmount these obstacles by developing a drug delivery system employing biopolymeric emulsion techniques to optimize the therapeutic efficacy of a natural anti-tumor agent, betulinic acid. More details can be found in article 2400283 by Bathabile Ramalapa, Suprakas Sinha Ray, and co-workers. Suprakas Sinha Ray designed the cover art in collaboration with the team at INMYWORK Studio.
期刊介绍：
Macromolecular Materials and Engineering is the high-quality polymer science journal dedicated to the design, modification, characterization, processing and application of advanced polymeric materials, including membranes, sensors, sustainability, composites, fibers, foams, 3D printing, actuators as well as energy and electronic applications.
Macromolecular Materials and Engineering is among the top journals publishing original research in polymer science.
The journal presents strictly peer-reviewed Research Articles, Reviews, Perspectives and Comments.
ISSN: 1438-7492 (print). 1439-2054 (online).
Readership:Polymer scientists, chemists, physicists, materials scientists, engineers
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