Synthesis and Characterization of a Pla Scaffold with Pseudoboehmite and Graphene Oxide Nanofillers Added.

IF 4.3 3区 材料科学 Q2 CHEMISTRY, MULTIDISCIPLINARY Nanomaterials Pub Date : 2025-01-22 DOI:10.3390/nano15030167
Rafael Vieira Maidana, Antônio Hortêncio Munhoz, Filipe Figueiredo Ramos, Alex Lopes de Oliveira, José César de Souza Almeida Neto, Victor Inácio de Oliveira, Bruno Luis Soares de Lima, Fábio Jesus Moreira de Almeida
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Abstract

In cases of severe injuries or burns, skin grafts (scaffolds) are often required as skin substitutes. In order not to harm the patient or the donor, biodegradable and biocompatible materials are used, which validates the search for heterografts such as poly (L-lactic acid)-PLA. However, natural polymers applied to the skin suffer great degradation in environments with large amounts of carbon and water or via binders with considerable resistivity, which implies little durability due to their low ductility. For the proposal, this work investigates PLA-based scaffolds modified with a mixture of pseudoboehmite (PB) and graphene oxide (GO), produced via the sol-gel route. The nanomaterials are incorporated into the polymer at different loadings, seeking to improve mechanical and thermal properties. Analyses via SEM, EDS, and XRD confirm the presence and distribution of these fillers. Tensile and flexural tests indicate that adding the filler can increase stress resistance, prevent deformations before failure, and increase toughness when compared to pure PLA.

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添加假薄水铝石和氧化石墨烯纳米填料的Pla支架的合成与表征。
在严重损伤或烧伤的情况下,通常需要皮肤移植物(支架)作为皮肤替代品。为了不伤害患者或供体,使用了可生物降解和生物相容性的材料,这验证了寻找异种移植物如聚(l -乳酸)-PLA的可行性。然而,应用于皮肤的天然聚合物在含有大量碳和水的环境中或通过具有相当电阻率的粘合剂遭受严重降解,这意味着由于其低延展性而导致耐久性差。对于该提案,本工作研究了通过溶胶-凝胶途径生产的假薄水铝石(PB)和氧化石墨烯(GO)混合物修饰的pla基支架。纳米材料以不同的负载加入到聚合物中,以寻求改善机械和热性能。通过SEM, EDS和XRD分析证实了这些填料的存在和分布。拉伸和弯曲试验表明,与纯PLA相比,添加填料可以提高抗应力,在破坏前防止变形,并提高韧性。
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来源期刊
Nanomaterials
Nanomaterials NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
CiteScore
8.50
自引率
9.40%
发文量
3841
审稿时长
14.22 days
期刊介绍: Nanomaterials (ISSN 2076-4991) is an international and interdisciplinary scholarly open access journal. It publishes reviews, regular research papers, communications, and short notes that are relevant to any field of study that involves nanomaterials, with respect to their science and application. Thus, theoretical and experimental articles will be accepted, along with articles that deal with the synthesis and use of nanomaterials. Articles that synthesize information from multiple fields, and which place discoveries within a broader context, will be preferred. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental or methodical details, or both, must be provided for research articles. Computed data or files regarding the full details of the experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. Nanomaterials is dedicated to a high scientific standard. All manuscripts undergo a rigorous reviewing process and decisions are based on the recommendations of independent reviewers.
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