Changes in Non-invasive Myocardial Stroke Work Related to Variation in Pacing Sites and Heart Rates in Adolescents.

IF 1.4 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pediatric Cardiology Pub Date : 2026-02-01 Epub Date: 2025-02-12 DOI:10.1007/s00246-025-03798-5

Shankar Baskar, Hieu T Ta, David S Spar, Richard J Czosek, Nicholas J Ollberding, Justin T Tretter

{"title":"Changes in Non-invasive Myocardial Stroke Work Related to Variation in Pacing Sites and Heart Rates in Adolescents.","authors":"Shankar Baskar, Hieu T Ta, David S Spar, Richard J Czosek, Nicholas J Ollberding, Justin T Tretter","doi":"10.1007/s00246-025-03798-5","DOIUrl":null,"url":null,"abstract":"<p><p>Non-invasive assessment of myocardial work is a newly described technique to assess myocardial energetics. This has not been previously studied to assess the effects of right ventricular pacing at different sites or at different heart rates in children. We aimed to study the effects of right ventricular apical, septal, and His bundle pacing on myocardial work along with the effects of increasing heart rate. This was a prospective pilot study performed on six patients with structurally normal hearts and function following an electrophysiology study. Global work index and global work efficiency was highest during His pacing and lowest during right ventricular apical pacing. The global constructive work, index, and efficiency were progressively worse with increasing heart rates. In this prospective pilot study, we demonstrated that myocardial work indices differ depending on myocardial activation pattern and at different heart rates in pediatric patients. Myocardial performance as assessed by myocardial work efficiency is worse when pacing is performed at the right ventricular apex when compared to His and right ventricular septal pacing. Myocardial performance can be affected by higher heart rates, following a work-frequency relationship.</p>","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"557-563"},"PeriodicalIF":1.4000,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12855315/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00246-025-03798-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/12 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Non-invasive assessment of myocardial work is a newly described technique to assess myocardial energetics. This has not been previously studied to assess the effects of right ventricular pacing at different sites or at different heart rates in children. We aimed to study the effects of right ventricular apical, septal, and His bundle pacing on myocardial work along with the effects of increasing heart rate. This was a prospective pilot study performed on six patients with structurally normal hearts and function following an electrophysiology study. Global work index and global work efficiency was highest during His pacing and lowest during right ventricular apical pacing. The global constructive work, index, and efficiency were progressively worse with increasing heart rates. In this prospective pilot study, we demonstrated that myocardial work indices differ depending on myocardial activation pattern and at different heart rates in pediatric patients. Myocardial performance as assessed by myocardial work efficiency is worse when pacing is performed at the right ventricular apex when compared to His and right ventricular septal pacing. Myocardial performance can be affected by higher heart rates, following a work-frequency relationship.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

无创心肌卒中功的变化与青少年起搏部位和心率的变化有关。

无创心肌功评价是一种评价心肌能量学的新技术。以前还没有研究评估儿童在不同部位或不同心率时右心室起搏的影响。我们的目的是研究右心室心尖、间隔和他束起搏对心肌功能的影响以及心率增加的影响。这是一项前瞻性先导研究，在电生理学研究之后，对6名心脏结构和功能正常的患者进行了研究。整体工作指数和整体工作效率在心脏起搏时最高，在右室尖室起搏时最低。随着心率的增加，整体建设性工作、指数和效率逐渐变差。在这项前瞻性先导研究中，我们证明了心肌工作指数的不同取决于心肌激活模式和不同的心率在儿科患者。与右室间隔起搏和右心尖起搏相比，在右心尖起搏时，心肌工作效率评估的心肌表现更差。心肌表现会受到高心率的影响，这是一种工作频率关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Pediatric Cardiology 医学-小儿科

CiteScore

3.30

自引率

6.20%

发文量

258

审稿时长

12 months

期刊介绍： The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.