Validation of nonhome discharge risk score after elective infrainguinal bypass surgery

IF 3.6 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE Journal of Vascular Surgery Pub Date : 2025-07-01 Epub Date: 2025-02-11 DOI:10.1016/j.jvs.2025.02.003
Elizabeth E. Raby BS , Richard D. Gutierrez MD , Zachary A. Matthay MD , Warren J. Gasper MD , Jade Hiramoto MD , Michael S. Conte MD , James C. Iannuzzi MD, MPH
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Abstract

Objective

Nonhome discharge (NHD) contributes to poor patient quality of life and health care costs. Prior Vascular Study Group of New England database-based analysis developed a novel risk score for NHD after infrainguinal lower extremity bypass (LEB). Still, it has yet to be validated in an external dataset. This study hypothesized that the LEB NHD risk score would be externally validated using unique single institutional data.

Methods

A single institutional quaternary center electronic data warehouse was queried for elective LEB cases from 2012 to 2020. The primary end point was NHD, defined as discharge to a skilled nursing facility or acute rehabilitation center. This analysis excluded inpatient deaths. A previously developed risk score was applied. The risk score's predictive ability for NHD was assessed using a logistic regression, c-statistic, and Hosmer-Lemeshow test. The risk score was then categorized as low risk (score <5), moderate risk (score 5-9), and high risk (score >9) for NHD.

Results

Among 242 included patients, NHD occurred in 22% of cases. The mean age of this cohort was 69 years. The cohort was 38.0% female and 26.4% non-White. The NHD proportion by risk category was 34.0% in high-risk, 26.0% in moderate-risk, and 4.0% in low-risk cases. High-risk cases represented 17% of the population and 27% of all NHD. On logistic regression, higher-risk groups had significantly higher odds of NHD than the low-risk category (moderate risk: odds ratio [OR], 8.8; 95% confidence itnerval [CI], 2.02-38.4; P = .004; high risk: OR, 13.0; 95% CI, 2.7-63.1; P = .001). The risk score successfully predicted NHD with a c-statistic of 0.702 and Hosmer-Lemeshow P value of .748, suggesting the model fit the data.

Conclusions

A novel NHD risk score was validated in an external single-institutional dataset. This risk score could be used to provide better pre-operative counseling and streamline postdischarge planning. Future studies should prospectively validate the NHD risk score.
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择期腹股沟下搭桥手术后非居家出院风险评分的验证。
目的:非家庭出院(NHD)导致患者生活质量下降和医疗费用增加。新英格兰先前血管研究小组基于数据库的分析开发了一种新的风险评分,如表1所示,用于腹股沟下下肢旁路手术(LEB)后的NHD。尽管如此,它还没有在外部数据集中得到验证。本研究假设LEB NHD风险评分将使用唯一的单一机构数据进行外部验证。方法:对2012-2020年单个机构第四中心电子数据仓库的选择性LEB病例进行查询。主要终点是NHD,定义为出院到专业护理机构或急性康复中心。该分析排除了住院患者死亡。应用先前开发的风险评分(表1)。使用逻辑回归、c统计和Hosmer-Lemeshow检验评估风险评分对NHD的预测能力。然后将NHD的风险评分归类为低风险(得分9)。结果:242例纳入的患者中,NHD发生率为22%。该队列的平均年龄为69岁。研究对象中女性占38%,非白人占26.4%。高危病例NHD比例为34%,中危病例为26%,低危病例为4%。高危病例占总人口的17%,占所有NHD的27%。经logistic回归分析,高危组NHD的发生率明显高于低危组(中度危险度OR:8.8, CI 2.02-38.4, p=0.004,高危组OR: 13.0, CI:2.7-63.1, p=0.001)。风险评分成功预测NHD, c统计量为0.702,Hosmer-Lemeshow p=0.748,表明模型与数据拟合。结论:在外部单一机构数据集中验证了一种新的非家庭出院风险评分。该风险评分可用于提供更好的术前咨询和简化出院后计划。未来的研究应前瞻性地验证NHD风险评分。
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来源期刊
CiteScore
7.70
自引率
18.60%
发文量
1469
审稿时长
54 days
期刊介绍: Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.
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