Transforaminal Full-Endoscopic Surgery for Lumbar Foraminal Pathologies: A Comparative Clinical Effectiveness Study.

IF 3.9 2区 医学 Q1 CLINICAL NEUROLOGY Neurosurgery Pub Date : 2025-03-01 Epub Date: 2025-02-14 DOI:10.1227/neu.0000000000003337
Kosuke Sugiura, Cathryn Payne, Nguyen T Tran, Jannik Leyendecker, John Ogunlade, Mary LaVanne, Peter B Derman, Robert Quon, Albert E Telfeian, Christoph P Hofstetter
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Abstract

Background and objectives: Full-endoscopic surgery is increasingly used for treating lumbar foraminal pathologies, though the specific indications remain unclear. This study aims to evaluate patient-reported outcomes after transforaminal full-endoscopic spine surgery for various lumbar foraminal conditions.

Methods: Multicenter cohort study of patients with intervertebral lumbar foraminal pathology who underwent full-endoscopic decompression at four medical centers. Postoperative patient-reported outcomes, including low back and leg pain as well as Oswestry Disability Index (ODI) scores, were prospectively tracked using a mobile app for 6 months. Six-month outcome measures (patient-reported outcome measures) were used as the primary outcome variable to determine treatment effectiveness regarding various foraminal pathologies.

Results: A total of 83 patients with a mean age of 57.04 ± 1.63 years were included. The most common operative levels were L4/5 for transforaminal endoscopic discectomies (59.6%) and L5/S1 for endoscopic foraminotomies (58.1%). Endoscopic discectomies resulted in significant improvements in Visual Analog Scale scores for low back pain (from 5.85 ± 0.43 to 3.02 ± 0.41; P < .001), leg pain (from 6.66 ± 0.34 to 3.12 ± 0.57; P < .001), and ODI scores (from 24.39 ± 1.35 to 12.32 ± 176; P < .001). Endoscopic foraminotomies also resulted in significant improvements in Visual Analog Scale scores for low back pain (from 5.58 ± 0.53 to 3.68 ± 0.58; P < .001) and leg pain (from 6.42 ± 0.47 to 4.21 ± 0.58; P < .001), as well as ODI scores (from 19.28 ± 1.41 to 14.67 ± 2.03; P < .01). The amount of improvement was independent of the severity of foraminal stenosis, as determined on preoperative MRI. However, vertical foraminal stenosis was associated with the lowest treatment response rate.

Conclusion: Endoscopic foraminotomies result in clinically meaningful symptomatic improvement for most lumbar foraminal pathologies. However, the effectiveness of decompression surgery for vertical foraminal stenosis is limited and requires further investigation.

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经椎间孔全内窥镜手术治疗腰椎椎间孔病变:临床疗效比较研究。
背景和目的:尽管具体适应症尚不清楚,但全内窥镜手术越来越多地用于治疗腰椎椎间孔病变。本研究旨在评估经椎间孔全内窥镜脊柱手术治疗各种腰椎椎间孔疾病后患者报告的结果。方法:对在四家医疗中心接受全内窥镜减压的腰椎间孔病变患者进行多中心队列研究。术后患者报告的结果,包括腰痛和腿部疼痛以及Oswestry残疾指数(ODI)评分,使用移动应用程序进行前瞻性跟踪6个月。六个月的结果测量(患者报告的结果测量)被用作主要结果变量,以确定针对各种椎间孔病理的治疗效果。结果:共纳入83例患者,平均年龄57.04±1.63岁。经椎间孔内窥镜椎间盘切除术最常见的手术水平为L4/5(59.6%)和L5/S1(58.1%)。内镜下椎间盘切除术导致腰痛视觉模拟量表评分显著改善(从5.85±0.43到3.02±0.41;P < 0.001),腿痛(从6.66±0.34降至3.12±0.57;P < 0.001), ODI评分从24.39±1.35降至12.32±176;P < 0.001)。内窥镜椎间孔切开术也显著改善了腰痛的视觉模拟量表评分(从5.58±0.53到3.68±0.58;P < 0.001)和腿痛(从6.42±0.47降至4.21±0.58;P < 0.001), ODI评分从19.28±1.41降至14.67±2.03;P < 0.01)。术前MRI检查显示,改善程度与椎间孔狭窄的严重程度无关。然而,垂直椎间孔狭窄与最低的治疗有效率相关。结论:内窥镜椎间孔切开术对大多数腰椎椎间孔病变有临床意义的症状改善。然而,减压手术治疗垂直椎间孔狭窄的有效性是有限的,需要进一步研究。
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来源期刊
Neurosurgery
Neurosurgery 医学-临床神经学
CiteScore
8.20
自引率
6.20%
发文量
898
审稿时长
2-4 weeks
期刊介绍: Neurosurgery, the official journal of the Congress of Neurological Surgeons, publishes research on clinical and experimental neurosurgery covering the very latest developments in science, technology, and medicine. For professionals aware of the rapid pace of developments in the field, this journal is nothing short of indispensable as the most complete window on the contemporary field of neurosurgery. Neurosurgery is the fastest-growing journal in the field, with a worldwide reputation for reliable coverage delivered with a fresh and dynamic outlook.
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