Lipedema awareness in fibromyalgia.

IF 1.5 Phlebology Pub Date : 2025-09-01 Epub Date: 2025-02-14 DOI:10.1177/02683555251321042
Elzem Bolkan Günaydın, Zeliha Ünlü, Saime Ay, Tolga Oğuz Karapınar
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Abstract

ObjectivesTo evaluate the presence of lipedema and lipedema-related factors in fibromyalgia patients.MethodsThe study included 100 female patients over the age of 18 who met the fibromyalgia diagnostic criteria. The patients were evaluated for the presence/stages of lipedema. The body mass index (BMI), waist-hip ratio, waist-height ratio, and presence of hematoma tendency/telangiectasias were recorded. Patients were asked to mark the severity of their pain (widespread/on lipedema) on a 10 cm visual analog scale (VAS). The ACR 2016 Fibromyalgia Diagnostic Criteria, The Beck Depression Inventory (BDI), and The Revised Fibromyalgia Impact Questionnaire were applied.ResultsLipedema was observed in 50% of the patients (58% Stage 1 lipedema). In the lipedema group, age, duration of fibromyalgia diagnosis, hematoma tendency/presence of telangiectasias (for all; p < .001), menopausal status (p = .004), BDI score (p = .04), BMI (p = .02), history of medication for fibromyalgia (p = .01) were higher, and age at menarche (p = .01) was lower. Lipedema stage was moderately positively correlated with BMI, number of pregnancies (for both; r:0.53 p < .001) and waist-height ratio (r:0.43 p:0.002), while VAS-lipedema pain intensity was strongly positively correlated with VAS-widespread pain intensity (r:0.62 p < .001), and moderately positively correlated with symptom severity score (r:0.55 p < .001), BMI (r:0.54 p < .001), and fibromyalgia severity score (r:0.51 p < .001). Long fibromyalgia diagnosis time (p: 0.005), and low age at menarche (p: 0.05) were significant risk factors for the presence of lipedema.ConclusionsLipedema is common in fibromyalgia patients. Long fibromyalgia diagnosis time and low age at menarche are significant risk factors for the presence of lipedema.

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纤维肌痛的脂水肿意识。
目的:探讨纤维肌痛患者是否存在脂肪水肿及相关因素。方法:本研究纳入100例18岁以上符合纤维肌痛诊断标准的女性患者。评估患者是否存在脂水肿/脂水肿分期。记录体重指数(BMI)、腰臀比、腰高比和血肿倾向/毛细血管扩张的存在。患者被要求在10厘米视觉模拟量表(VAS)上标记疼痛的严重程度(广泛/脂水肿)。采用ACR 2016纤维肌痛诊断标准、贝克抑郁量表(BDI)和修订后的纤维肌痛影响问卷。结果:50%的患者出现脂肪水肿(58%为1期脂肪水肿)。在脂水肿组,年龄,纤维肌痛诊断的持续时间,血肿倾向/毛细血管扩张的存在(所有;p < 0.001)、绝经状态(p = 0.004)、BDI评分(p = 0.04)、BMI (p = 0.02)、纤维肌痛用药史(p = 0.01)较高,初潮年龄(p = 0.01)较低。脂水肿阶段与BMI、怀孕次数(两者;r:0.53 p < .001)和腰高比(r:0.43 p:0.002),而vas -脂水肿疼痛强度与vas -广泛疼痛强度(r:0.62 p < .001)呈强正相关,与症状严重程度评分(r:0.55 p < .001)、BMI (r:0.54 p < .001)、纤维肌痛严重程度评分(r:0.51 p < .001)呈中度正相关。纤维肌痛诊断时间长(p: 0.005)、月经初潮年龄低(p: 0.05)是脂水肿发生的重要危险因素。结论:脂肪水肿在纤维肌痛患者中很常见。纤维肌痛诊断时间长和月经初潮年龄低是脂水肿存在的重要危险因素。
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