Christina Barda , Maria-Eleni Grafakou , Joerg Heilmann , Helen Skaltsa
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引用次数: 0
Abstract
Within the genus Crepis of the Asteraceae family (Cichorieae), Crepis heldreichiana (Kuntze) Greuter is recognized as a native plant in the Greek flora, with a distribution limited to the Taigetos and Parnonas mountains of the Peloponnese.
Taking into consideration the restricted geographic range and the unexplored chemical profile of C. heldreichiana. This study was designed to unveil its phytochemical profile revealing 13 compounds, among which four are identified as sesquiterpene lactones, including a previously unreported one, as well as an apocaroteonoid, while the remaining are primarily phenolic derivatives.
Various spectrometric and spectroscopic techniques were employed to elucidate the structures of the isolated compounds. The relative configurations of the compounds were established through analysis of NMR spectroscopic and HRESIMS spectrometric data, complemented by CD spectroscopic measurements.
期刊介绍：
Phytochemistry Letters invites rapid communications on all aspects of natural product research including:
• Structural elucidation of natural products
• Analytical evaluation of herbal medicines
• Clinical efficacy, safety and pharmacovigilance of herbal medicines
• Natural product biosynthesis
• Natural product synthesis and chemical modification
• Natural product metabolism
• Chemical ecology
• Biotechnology
• Bioassay-guided isolation
• Pharmacognosy
• Pharmacology of natural products
• Metabolomics
• Ethnobotany and traditional usage
• Genetics of natural products
Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.
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