Evaluation of wear, corrosion, and biocompatibility of a novel biomedical TiZr-based medium entropy alloy

IF 3.3 2区医学 Q2 ENGINEERING, BIOMEDICAL Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-02-13 DOI:10.1016/j.jmbbm.2025.106951

Dandan Zhu , Xiaoqiang Li , Shaoyu Chai , Tien-Shee Chee , Chaerin Kim , Liang Li , Dexue Liu

{"title":"Evaluation of wear, corrosion, and biocompatibility of a novel biomedical TiZr-based medium entropy alloy","authors":"Dandan Zhu , Xiaoqiang Li , Shaoyu Chai , Tien-Shee Chee , Chaerin Kim , Liang Li , Dexue Liu","doi":"10.1016/j.jmbbm.2025.106951","DOIUrl":null,"url":null,"abstract":"<div><div>As a promising material for medical implants, the Ti40Zr40Nb5Ta12Sn3 medium entropy alloy (MEA) shows potential for biomedical applications. This study investigates its wear and corrosion behavior in simulated biological environments, including artificial saliva (AS), simulated blood (SB), and simulated body fluid (SBF). Electrochemical tests revealed excellent corrosion resistance in AS solution, with a higher corrosion potential (−0.31420 V) and a lower corrosion current density (2.613 × 10⁻⁷ A·cm⁻2). Wear tests showed that friction coefficients ranked as μAS > μSBF > μSB, while wear rates followed δSBF > δSB > δAS, highlighting the impact of bio-lubricants composition on tribological behavior. In particular, the alloy exhibited a higher ion release rate in the SBF solution, with ion concentrations approximately 2.5 times greater than those in the AS solution. In contrast, the alloy in the AS solution maintained a more stable passivation film, thus reducing ion release and enhancing both wear and corrosion resistance of the alloy. The biocompatibility test further confirmed that it has good cell adhesion and proliferation ability. This study provides valuable insights into the synergistic effects of wear and corrosion on the alloy in simulated physiological environments.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"165 ","pages":"Article 106951"},"PeriodicalIF":3.3000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Mechanical Behavior of Biomedical Materials","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1751616125000670","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

As a promising material for medical implants, the Ti₄₀Zr₄₀Nb₅Ta₁₂Sn₃ medium entropy alloy (MEA) shows potential for biomedical applications. This study investigates its wear and corrosion behavior in simulated biological environments, including artificial saliva (AS), simulated blood (SB), and simulated body fluid (SBF). Electrochemical tests revealed excellent corrosion resistance in AS solution, with a higher corrosion potential (−0.31420 V) and a lower corrosion current density (2.613 × 10⁻⁷ A·cm⁻²). Wear tests showed that friction coefficients ranked as μ_AS > μ_SBF > μ_SB, while wear rates followed δ_SBF > δ_SB > δ_AS, highlighting the impact of bio-lubricants composition on tribological behavior. In particular, the alloy exhibited a higher ion release rate in the SBF solution, with ion concentrations approximately 2.5 times greater than those in the AS solution. In contrast, the alloy in the AS solution maintained a more stable passivation film, thus reducing ion release and enhancing both wear and corrosion resistance of the alloy. The biocompatibility test further confirmed that it has good cell adhesion and proliferation ability. This study provides valuable insights into the synergistic effects of wear and corrosion on the alloy in simulated physiological environments.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.