Simple and disposable device based on gold nanoparticles modified screen-printed carbon electrode for detection of ciprofloxacin

IF 2.6 4区化学 Q3 ELECTROCHEMISTRY Journal of Solid State Electrochemistry Pub Date : 2024-10-28 DOI:10.1007/s10008-024-06119-7

Daniela Nunes da Silva, Thaís Cristina de Oliveira Cândido, Arnaldo César Pereira

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Abstract

This study describes the development and characterization of an electrochemical sensor based on gold nanoparticles (AuNPs) immobilized on a screen-printed carbon electrode (SPCE) supported by polyethylene terephthalate (PET) for ciprofloxacin (CPX) detection. The SPCE-AuNPs sensor was fabricated using optimized carbonaceous material-based inks for the working and counter electrodes, while silver/silver chloride ink was employed for the quasi-reference electrode. Electrochemical characterization revealed a significant 223% increase in CPX oxidation current intensity compared to the unmodified SPCE electrode. Electrochemical impedance spectroscopy (EIS) confirmed this improvement, showing a decrease in charge transfer resistance (Rct) from 0.225 kΩ for SPCE to 0.125 kΩ for SPCE-AuNPs. Under optimized conditions utilizing differential pulse voltammetry (DPV), the sensor exhibited a linear range of 0.4 to 88.0 μmol L⁻¹, a limit of detection of 0.12 μmol L⁻¹, and a limit of quantification of 0.4 μmol L⁻¹. The developed method was applied to determine CPX in water and pharmaceutical formulation samples, achieving excellent recovery values ranging from 96 to 104%.

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来源期刊

Journal of Solid State Electrochemistry 工程技术-电化学

CiteScore

4.80

自引率

4.00%

发文量

227

审稿时长

4.1 months

期刊介绍： The Journal of Solid State Electrochemistry is devoted to all aspects of solid-state chemistry and solid-state physics in electrochemistry. The Journal of Solid State Electrochemistry publishes papers on all aspects of electrochemistry of solid compounds, including experimental and theoretical, basic and applied work. It equally publishes papers on the thermodynamics and kinetics of electrochemical reactions if at least one actively participating phase is solid. Also of interest are articles on the transport of ions and electrons in solids whenever these processes are relevant to electrochemical reactions and on the use of solid-state electrochemical reactions in the analysis of solids and their surfaces. The journal covers solid-state electrochemistry and focusses on the following fields: mechanisms of solid-state electrochemical reactions, semiconductor electrochemistry, electrochemical batteries, accumulators and fuel cells, electrochemical mineral leaching, galvanic metal plating, electrochemical potential memory devices, solid-state electrochemical sensors, ion and electron transport in solid materials and polymers, electrocatalysis, photoelectrochemistry, corrosion of solid materials, solid-state electroanalysis, electrochemical machining of materials, electrochromism and electrochromic devices, new electrochemical solid-state synthesis. The Journal of Solid State Electrochemistry makes the professional in research and industry aware of this swift progress and its importance for future developments and success in the above-mentioned fields.