Enhanced recovery after surgery in the perioperative period promotes recovery of cervical cancer patients undergoing transabdominal radical resection.

IF 1.6 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL American journal of translational research Pub Date : 2025-01-15 eCollection Date: 2025-01-01 DOI:10.62347/IOZV1140
Di-Ling Li, Wei Li, Zhi-Jun Chen
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Abstract

Objective: To explore the effects of enhanced recovery after surgery (ERAS) during the perioperative period in patients undergoing transabdominal radical resection of cervical cancer.

Methods: A total of 114 patients who underwent transabdominal radical resection for cervical cancer at the Red Cross Hospital of Yulin City from January 2020 to December 2023 were retrospectively reviewed. Patients were divided into two groups based on the perioperative intervention method: the ERAS group (n = 51) received ERAS-based management, while the control group (CG, n = 63) received conventional perioperative management. Key outcomes compared included postoperative recovery time, complication rates, hospital stay duration, T lymphocyte levels, and patient satisfaction.

Results: Postoperative anal exhaust time, first defecation time, ambulation time, and hospital stay were significantly shorter in the ERAS group compared to the CG group (all P < 0.05). The ERAS group also showed earlier catheter removal, faster bladder function recovery, and lower residual urine volume (all P < 0.05). Postoperative serum levels of C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) increased in both groups but were significantly lower in the ERAS group (all P < 0.05). The ERAS group demonstrated improved postoperative quality of life (QLQ-C30 scores), reduced Pittsburgh Sleep Quality Index (PSQI) and Self-Rating Anxiety Scale (SAS) scores, and a significantly lower incidence of postoperative urinary tract infection (7.84% vs. 30.16%, all P < 0.05). Treatment satisfaction was higher in the ERAS group (96.08% vs. 76.19%, P < 0.05).

Conclusion: ERAS effectively promotes gastrointestinal function recovery, reduces hospital stay, accelerates postoperative rehabilitation, and enhances patient satisfaction in cervical cancer patients undergoing transabdominal radical resection. It is safe, economical, and has an efficient approach that supports wider clinical adoption.

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围手术期术后恢复的增强促进了经腹根治术宫颈癌患者的康复。
目的:探讨经腹宫颈癌根治术围手术期提高术后恢复(ERAS)的效果。方法:回顾性分析2020年1月至2023年12月榆林市红十字会医院经腹宫颈癌根治术患者114例。根据围手术期干预方式将患者分为两组:ERAS组(n = 51)采用ERAS为主的围手术期管理,对照组(n = 63)采用常规围手术期管理。比较的主要结果包括术后恢复时间、并发症发生率、住院时间、T淋巴细胞水平和患者满意度。结果:ERAS组术后肛门排气时间、首次排便时间、下床时间、住院时间均显著短于CG组(P < 0.05)。ERAS组拔管时间较早,膀胱功能恢复较快,残余尿量较低(P < 0.05)。两组术后血清c反应蛋白(CRP)、白细胞介素-6 (IL-6)、肿瘤坏死因子-α (TNF-α)水平均升高,ERAS组显著降低(均P < 0.05)。ERAS组术后生活质量(QLQ-C30评分)改善,匹兹堡睡眠质量指数(PSQI)和焦虑自评量表(SAS)评分降低,术后尿路感染发生率显著降低(7.84% vs. 30.16%,均P < 0.05)。ERAS组治疗满意度较高(96.08%比76.19%,P < 0.05)。结论:ERAS可有效促进宫颈癌经腹根治术患者胃肠功能恢复,缩短住院时间,加快术后康复,提高患者满意度。它安全、经济、有效,支持更广泛的临床应用。
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来源期刊
American journal of translational research
American journal of translational research ONCOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
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552
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