Masquelet technique using an allogeneic cortical bone graft for a large bone defect: A case report.

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL World Journal of Clinical Cases Pub Date : 2025-02-16 DOI:10.12998/wjcc.v13.i5.99963
Hai-Yang Zong, Yu Liu, Xing Yin, Wei Zhou, Nan Li
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Abstract

Background: The induced-membrane technique was initially described by Masquelet as an effective treatment for large bone defects, especially those caused by infection. Here, we report a case of chronic osteomyelitis of the radius associated with a 9 cm bone defect, which was filled with a large allogeneic cortical bone graft from a bone bank. Complete bony union was achieved after 14 months of follow-up. Previous studies have used autogenous bone as the primary bone source for the Masquelet technique; in our case, the exclusive use of allografts is as successful as the use of autologous bone grafts. With the advent of bone banks, it is possible to obtain an unlimited amount of allograft, and the Masquelet technique may be further improved based on this new way of bone grafting.

Case summary: In this study, we reported a case of repair of a long bone defect in a 40-year-old male patient, which was characterized by the utilization of allograft cortical bone combined with the Masquelet technique for the treatment of the patient's long bone defect in the forearm. The patient's results of functional recovery of the forearm were surprising, which further deepens the scope of application of Masquelet technique and helps to strengthen the efficacy of Masquelet technique in the treatment of long bones indeed.

Conclusion: Allograft cortical bone combined with the Masquelet technique provides a new method of treatment to large bone defect.

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异体皮质骨移植面罩小波技术治疗大面积骨缺损1例报告。
背景:Masquelet最初将诱导膜技术描述为治疗大型骨缺损的有效方法,特别是那些由感染引起的骨缺损。在此,我们报告一例慢性桡骨骨髓炎伴9厘米骨缺损的病例,该骨缺损由来自骨库的大异体皮质骨移植物填充。随访14个月后骨完全愈合。先前的研究使用自体骨作为Masquelet技术的主要骨源;在我们的病例中,同种异体骨移植与自体骨移植一样成功。随着骨库的出现,获得无限量的同种异体移植物成为可能,Masquelet技术可能在此基础上得到进一步的改进。病例总结:在本研究中,我们报告了一例40岁男性患者长骨缺损的修复,其特点是利用同种异体皮质骨结合Masquelet技术治疗患者前臂长骨缺损。患者前臂功能恢复的结果令人惊讶,这进一步加深了Masquelet技术的应用范围,确实有助于加强Masquelet技术在长骨治疗中的疗效。结论:同种异体皮质骨联合Masquelet技术为治疗大面积骨缺损提供了一种新的方法。
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World Journal of Clinical Cases
World Journal of Clinical Cases Medicine-General Medicine
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期刊介绍: The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.
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