Masquelet technique using an allogeneic cortical bone graft for a large bone defect: A case report.

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL World Journal of Clinical Cases Pub Date : 2025-02-16 DOI:10.12998/wjcc.v13.i5.99963
Hai-Yang Zong, Yu Liu, Xing Yin, Wei Zhou, Nan Li
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Abstract

Background: The induced-membrane technique was initially described by Masquelet as an effective treatment for large bone defects, especially those caused by infection. Here, we report a case of chronic osteomyelitis of the radius associated with a 9 cm bone defect, which was filled with a large allogeneic cortical bone graft from a bone bank. Complete bony union was achieved after 14 months of follow-up. Previous studies have used autogenous bone as the primary bone source for the Masquelet technique; in our case, the exclusive use of allografts is as successful as the use of autologous bone grafts. With the advent of bone banks, it is possible to obtain an unlimited amount of allograft, and the Masquelet technique may be further improved based on this new way of bone grafting.

Case summary: In this study, we reported a case of repair of a long bone defect in a 40-year-old male patient, which was characterized by the utilization of allograft cortical bone combined with the Masquelet technique for the treatment of the patient's long bone defect in the forearm. The patient's results of functional recovery of the forearm were surprising, which further deepens the scope of application of Masquelet technique and helps to strengthen the efficacy of Masquelet technique in the treatment of long bones indeed.

Conclusion: Allograft cortical bone combined with the Masquelet technique provides a new method of treatment to large bone defect.

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World Journal of Clinical Cases
World Journal of Clinical Cases Medicine-General Medicine
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期刊介绍: The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.
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