Advanced Technology Clinic Provides Personalized Approach to Pediatric Epilepsy Surgery: Early Data and Future Directions.

Missouri medicine Pub Date : 2025-01-01

Esra Pehlivan, John Zempel, Janette Coble, Sara Graves, Sean McEvoy, Matt Smyth, Kwee Liu Lin Thio, Christina Gurnett, Jarod Roland, Réjean M Guerriero, Stuart R Tomko

{"title":"Advanced Technology Clinic Provides Personalized Approach to Pediatric Epilepsy Surgery: Early Data and Future Directions.","authors":"Esra Pehlivan, John Zempel, Janette Coble, Sara Graves, Sean McEvoy, Matt Smyth, Kwee Liu Lin Thio, Christina Gurnett, Jarod Roland, Réjean M Guerriero, Stuart R Tomko","doi":"","DOIUrl":null,"url":null,"abstract":"Objective: Postoperative improvement in seizures may impact quality of life. We examined the relationship between reduced seizure burden and quality of life in a surgical epilepsy clinic.Methods: We reviewed data from all children who received epilepsy surgery at our center. Surgeries were classified as palliative or definitive based on the seizure outcome goals. We collected demographics, surgical data, Engel classification, and quality of life outcomes.Results: Between 2016 and 2024, 282 patients underwent 338 surgeries. In the definitive surgery group, 66 patients (58%) attained an Engel 1 outcome at six months and 46 patients (58%) at 24 months. In the palliative surgery group, six patients (7%) attained an Engel 1 outcome at six months. At 12 months, 75% of patients who attained Engel 1 reported lower depression scores.Conclusion: Improvement in seizure burden and quality of life outcomes following epilepsy surgery may be related. Further outcomes research is required.","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"39-45"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827649/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Missouri medicine","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: Postoperative improvement in seizures may impact quality of life. We examined the relationship between reduced seizure burden and quality of life in a surgical epilepsy clinic.

Methods: We reviewed data from all children who received epilepsy surgery at our center. Surgeries were classified as palliative or definitive based on the seizure outcome goals. We collected demographics, surgical data, Engel classification, and quality of life outcomes.

Results: Between 2016 and 2024, 282 patients underwent 338 surgeries. In the definitive surgery group, 66 patients (58%) attained an Engel 1 outcome at six months and 46 patients (58%) at 24 months. In the palliative surgery group, six patients (7%) attained an Engel 1 outcome at six months. At 12 months, 75% of patients who attained Engel 1 reported lower depression scores.

Conclusion: Improvement in seizure burden and quality of life outcomes following epilepsy surgery may be related. Further outcomes research is required.

微信好友朋友圈 QQ好友复制链接

本刊更多论文

先进技术诊所为小儿癫痫手术提供个性化方法：早期数据与未来方向

目的：癫痫发作的术后改善可能影响患者的生活质量。我们研究了外科癫痫诊所癫痫发作负担减轻与生活质量之间的关系。方法：我们回顾了所有在本中心接受癫痫手术的儿童的资料。手术根据癫痫结果目标分为姑息性和决定性两类。我们收集了人口统计学、手术数据、恩格尔分类和生活质量结果。结果：2016年至2024年，282例患者接受了338例手术。在最终手术组中，66例（58%）患者在6个月时达到Engel 1级，46例（58%）患者在24个月时达到Engel 1级。在姑息性手术组中，6名患者（7%）在6个月时达到Engel 1评分。在12个月时，75%达到Engel 1的患者报告抑郁评分较低。结论：癫痫手术后癫痫发作负担的改善可能与生活质量有关。需要进一步的结果研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊