{"title":"Report of the American Medical Association Interim Meeting.","authors":"Charles W Van Way","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"463-465"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autism Spectrum Disorder (ASD) is associated with a variety of inherited disorders, but most diagnoses have no identifiable genetic etiology. There has been a significant increase in the incidence of ASD diagnoses in the past three decades. The now-discredited vaccine theory of ASD causation has driven concerns over environmental exposures that may or may not lead to ASD. Here, I discuss the evidence for an underlying genetic basis for ASD, the evidence that environmental inputs could play a significant role ASD and potential treatments for associated symptoms.
{"title":"Autism Spectrum Disorder: Nature vs. Nurture.","authors":"Joel C Eissenberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autism Spectrum Disorder (ASD) is associated with a variety of inherited disorders, but most diagnoses have no identifiable genetic etiology. There has been a significant increase in the incidence of ASD diagnoses in the past three decades. The now-discredited vaccine theory of ASD causation has driven concerns over environmental exposures that may or may not lead to ASD. Here, I discuss the evidence for an underlying genetic basis for ASD, the evidence that environmental inputs could play a significant role ASD and potential treatments for associated symptoms.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"501-507"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Missouri Medicine Moments The 2025 Chronicle.","authors":"John C Hagan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"444-445"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Embracing Opportunities, Making Choices, and Focusing on the Mission.","authors":"Karen Edison","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"473-476"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abby L Cheng, Ryan Barker, David von Nordheim, Amy McQueen
As we pass the five-year mark since the COVID-19 pandemic hit, the prevalence of persistent (and often disabling) symptoms from the SARS-CoV-2 virus is estimated to be on par with the prevalence of heart disease. Yet, these Long COVID symptoms can masquerade as other conditions and/or normal aging, so it is believed that Long COVID is under-diagnosed and, as a result, under-treated. Although there is not yet a true cure for Long COVID, many patients benefit substantially from rehabilitation strategies, medications, and social support resources that are available in Missouri. The purpose of this article is to review the definition and epidemiology of Long COVID, provide practical guidance for Long COVID assessment and management especially in the primary care setting, and increase awareness of regional resources for people in Missouri who are living with Long COVID and for the clinicians who are caring for them.
{"title":"Long COVID: What is it? Who has it? What Are Treatment Resources in Missouri?","authors":"Abby L Cheng, Ryan Barker, David von Nordheim, Amy McQueen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As we pass the five-year mark since the COVID-19 pandemic hit, the prevalence of persistent (and often disabling) symptoms from the SARS-CoV-2 virus is estimated to be on par with the prevalence of heart disease. Yet, these Long COVID symptoms can masquerade as other conditions and/or normal aging, so it is believed that Long COVID is under-diagnosed and, as a result, under-treated. Although there is not yet a true cure for Long COVID, many patients benefit substantially from rehabilitation strategies, medications, and social support resources that are available in Missouri. The purpose of this article is to review the definition and epidemiology of Long COVID, provide practical guidance for Long COVID assessment and management especially in the primary care setting, and increase awareness of regional resources for people in Missouri who are living with Long COVID and for the clinicians who are caring for them.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"488-494"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Missouri's 2026 Legislative Session: A Pivotal Year for Physician-Led Care.","authors":"Rachel Bauer, Jacob Scott","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"458-460"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain implants are routinely used to treat movement disorders and other network disorders such as obsessive-compulsive disorder. Closed-loop intracranial brain stimulation systems can now detect neural biomarkers of disease in real-time and therapeutically stimulate the brain based on these signals. Research devices can measure neural data on the order of single neurons and transform these data, via machine learning algorithms, into cursor movements and keyboard clicks, so that a quadriplegic patient can control a robotic arm. It is still a challenge to find the important brain signals of interest, that encode a patient's intentions or needs. Furthermore, the ethics of developing devices that allow for human cognitive and physical enhancement should be a part of societal discussion. The hope is that artificial intelligence (AI) will continue to advance neurotechnology's role in human health.
{"title":"Brain Implants in the Age of Artificial Intelligence.","authors":"Bornali Kundu, Jamir Pleitez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Brain implants are routinely used to treat movement disorders and other network disorders such as obsessive-compulsive disorder. Closed-loop intracranial brain stimulation systems can now detect neural biomarkers of disease in real-time and therapeutically stimulate the brain based on these signals. Research devices can measure neural data on the order of single neurons and transform these data, via machine learning algorithms, into cursor movements and keyboard clicks, so that a quadriplegic patient can control a robotic arm. It is still a challenge to find the important brain signals of interest, that encode a patient's intentions or needs. Furthermore, the ethics of developing devices that allow for human cognitive and physical enhancement should be a part of societal discussion. The hope is that artificial intelligence (AI) will continue to advance neurotechnology's role in human health.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"517-524"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Running-Related Silent Atrial Flutter Presenting as a Stroke: A Marathoner's Tale.","authors":"Philip R Cohen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 6","pages":"477-481"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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