55 STUDY ON THE EFFECT OF MUSIC STRESS REDUCTION THERAPY ON SCHIZOPHRENIA OF FINANCIAL PRACTITIONERS

IF 5.3 1区 医学 Q1 PSYCHIATRY Schizophrenia Bulletin Pub Date : 2025-02-18 DOI:10.1093/schbul/sbaf007.055
Yiqin Xie
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Abstract

Background Workers in the financial industry generally face high pressure and high competition in the working environment, and have a high risk of mental health, including a high incidence of schizophrenia. Patients are usually accompanied by cognitive disorders, emotional disorders and impaired social functions, which seriously affect their quality of life and work ability. At present, the main use of drug intervention, but the efficacy is limited and may produce drug resistance and adverse reactions. Music therapy, which can regulate emotions, relieve stress and improve cognitive function, has gradually become a potential adjuvant therapy. However, there is a lack of systematic research on the effect of music therapy on financial practitioners with schizophrenia. The study evaluated the intervention effect of music therapy on the symptoms of financial practitioners, explored its application prospects and mechanisms, and provided references for personalized treatment programs. Methods A randomized controlled trial design was used to enroll 120 financial practitioners diagnosed with schizophrenia. All participants were randomly divided 1:1 into music therapy (n=60) and control (n=60) groups. The music therapy group received a 60-minute music therapy intervention twice a week for 12 weeks, in addition to their usual medication. Music therapy includes guided music listening, rhythmic interaction, and emotional expression activities that are personalized to match subjects’ musical preferences. The control group received only conventional drug treatment and no additional non-drug intervention. Symptom assessment measures included the Positive and Negative Syndrome Scale (PANSS) and the Beck Depression Inventory (BDI), which were measured at baseline, at week 6, and at the end of the intervention. In addition, acceptance and adherence to the intervention were assessed using satisfaction surveys. Results Baseline assessment showed no statistically significant differences in gender composition, mean age, duration of disease, or symptom score between the two groups (P>0.05). After the intervention, the total score of PANSS in the music therapy group was 62.3±12.4, while that in the control group was 73.5±11.2, which was significantly lower than that in the music therapy group (P<0.05). Further sub analysis showed that the negative symptom score of the music therapy group was 23.6±5.1, which was significantly lower than that of the control group (27.8±6.4, P<0.05). In terms of depressive symptoms, BDI scores in the music therapy group decreased from 28.5±6.8 to 18.4±5.2 at baseline (P<0.05), and BDI scores in the control group decreased from 28.7±7.0 to 23.4±6.7 (P<0.05). Discussion Our findings suggest that music stress reduction therapy significantly improves the clinical symptoms of financial practitioners with schizophrenia. By guiding emotional expression, relieving stress and promoting social interaction, music therapy has a positive effect on patients’ emotional regulation and recovery of social function. This non-invasive and personalized intervention is easy to accept and provides feasibility for the adjuvant treatment of schizophrenia. Future studies should further validate its long-term effects and explore its underlying biological mechanisms to provide more support for the integrated management of schizophrenia. Funding No. KJQN202304406; No. Z233173; No. K24ZG3260163.
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背景 金融行业从业人员普遍面临高压力、高竞争的工作环境,精神健康风险较高,其中精神分裂症发病率较高。患者通常伴有认知障碍、情感障碍、社会功能受损等症状,严重影响患者的生活质量和工作能力。目前主要采用药物干预,但疗效有限,且可能产生耐药性和不良反应。音乐疗法可以调节情绪、缓解压力、改善认知功能,已逐渐成为一种潜在的辅助疗法。然而,目前还缺乏音乐疗法对精神分裂症金融从业人员影响的系统研究。本研究评估音乐疗法对金融从业人员症状的干预效果,探讨其应用前景和机制,为个性化治疗方案提供参考。方法 采用随机对照试验设计,招募 120 名确诊为精神分裂症的金融从业人员。所有参与者按 1:1 随机分为音乐治疗组(60 人)和对照组(60 人)。音乐治疗组除常规药物治疗外,还接受每周两次、每次 60 分钟的音乐治疗干预,为期 12 周。音乐治疗包括有指导的音乐聆听、节奏互动和情感表达活动,这些活动根据受试者的音乐偏好进行个性化设计。对照组只接受常规药物治疗,不接受额外的非药物干预。症状评估指标包括正负综合量表(PANSS)和贝克抑郁量表(BDI),分别在基线、第 6 周和干预结束时进行测量。此外,还通过满意度调查对干预的接受度和坚持度进行了评估。结果 基线评估结果显示,两组患者在性别构成、平均年龄、病程或症状得分方面无统计学差异(P>0.05)。干预后,音乐治疗组的 PANSS 总分为 62.3±12.4,对照组为 73.5±11.2,明显低于音乐治疗组(P<0.05)。进一步的子分析表明,音乐治疗组的负性症状得分为 23.6±5.1,明显低于对照组(27.8±6.4,P<0.05)。在抑郁症状方面,音乐治疗组的 BDI 评分从基线时的 28.5±6.8 分降至 18.4±5.2 分(P<0.05),对照组的 BDI 评分从 28.7±7.0 分降至 23.4±6.7 分(P<0.05)。讨论 我们的研究结果表明,音乐减压疗法能明显改善精神分裂症金融从业人员的临床症状。通过引导情绪表达、缓解压力和促进社会交往,音乐疗法对患者的情绪调节和社会功能恢复具有积极作用。这种非侵入性的个性化干预易于接受,为精神分裂症的辅助治疗提供了可行性。今后的研究应进一步验证其长期疗效,探索其潜在的生物学机制,为精神分裂症的综合治疗提供更多支持。基金编号:KJQN202304406;编号:Z233173;编号:K24ZG3260163。
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来源期刊
Schizophrenia Bulletin
Schizophrenia Bulletin 医学-精神病学
CiteScore
11.40
自引率
6.10%
发文量
163
审稿时长
4-8 weeks
期刊介绍: Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. We view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. We will give new emphasis to translational reports which simultaneously highlight basic neurobiological mechanisms and clinical manifestations. Some of the Bulletin content is invited as special features or manuscripts organized as a theme by special guest editors. Most pages of the Bulletin are devoted to unsolicited manuscripts of high quality that report original data or where we can provide a special venue for a major study or workshop report. Supplement issues are sometimes provided for manuscripts reporting from a recent conference.
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