100 MRI IMAGE CLASSIFICATION AND SCHIZOPHRENIA RECOGNITION BASED ON IMPROVED ACNET

IF 4.8 1区 医学 Q1 PSYCHIATRY Schizophrenia Bulletin Pub Date : 2025-02-18 DOI:10.1093/schbul/sbaf007.100
Biao Yang
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Abstract

Background Schizophrenia is a complex neurodevelopmental disorder with significant heterogeneity, complex etiology, and an increasing prevalence worldwide. It faces significant challenges in clinical diagnosis and treatment, with missed and misdiagnosed cases occurring from time to time. Improving the diagnostic accuracy of schizophrenia is a prerequisite for early intervention and an important aspect of improving patients’ quality of life and reducing mortality rates. Studies have shown that the pathogenesis of schizophrenia may be related to changes in brain structure and tissue, and the use of neuroimaging technology can effectively provide auxiliary interventions for clinical diagnosis. With the development of machine learning algorithms in recent years, achieving automated medical diagnosis has become a current research hotspot. Considering the neglect of global features in traditional convolutional neural networks for extracting neuroimaging features, research proposes to improve them by using an adaptive asymmetric convolutional network (ACNet) to improve the accuracy of Magnetic Resonance Imaging (MRI) image classification and provide clinical intervention for the recognition of schizophrenia. Methods The study collected MRI image data of schizophrenia patients and healthy control subjects from public datasets and a tertiary hospital. The data was preprocessed using Matlab tools, including image slicing, weighted averaging, and extraction of texture features from gray level co-occurrence matrix. Afterwards, based on the convolutional neural network structure, sparse interaction mechanism and attention mechanism are introduced to enhance feature extraction ability and classification performance. Train the ACNet model using preprocessed MRI image data, and evaluate diagnostic results and classification accuracy using metrics such as accuracy and area under the curve. Results In Table 1, the improved model can effectively improve the classification accuracy of MRI images and the recognition accuracy of schizophrenia, with accuracy rates exceeding 94%, and the application effect is significant. Discussion Improving the MRI image classification method of ACNet provides a new approach for computer-aided diagnosis of schizophrenia. The model has shown significant accuracy in feature extraction and classification performance, with values exceeding 90%. MRI, as a non-invasive brain imaging technique, is widely used in brain examinations due to its ability to achieve arbitrary slicing in multiple directions. The core symptoms of schizophrenia include hallucinations, delusions, disordered thinking, and emotional apathy. These symptoms typically last for at least six months and severely affect the patient’s daily life and social functioning. The application of MRI in the identification of schizophrenia is becoming increasingly widespread. With the help of machine learning and deep learning techniques, MRI images can be automatically analyzed and classified to assist doctors in making more accurate diagnoses. The application of the improved method proposed in the study in MRI images can provide strong support for early intervention and precise treatment of the disease, help to better understand the neuropathological mechanism of schizophrenia, and improve the quality of life of patients.
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基于改进acnet的mri图像分类与精神分裂症识别
精神分裂症是一种复杂的神经发育障碍,具有显著的异质性,复杂的病因,并且在世界范围内的患病率不断上升。临床诊治面临重大挑战,漏诊和误诊病例时有发生。提高精神分裂症的诊断准确性是早期干预的先决条件,也是提高患者生活质量和降低死亡率的重要方面。研究表明,精神分裂症的发病机制可能与大脑结构和组织的改变有关,利用神经影像学技术可以有效地为临床诊断提供辅助干预。随着近年来机器学习算法的发展,实现医疗自动化诊断已成为当前的研究热点。针对传统卷积神经网络在提取神经影像学特征时忽略全局特征的问题,研究提出采用自适应非对称卷积网络(ACNet)对其进行改进,以提高磁共振成像(MRI)图像分类的准确性,为精神分裂症的识别提供临床干预。方法从公共数据库和某三级医院收集精神分裂症患者和健康对照者的MRI影像资料。利用Matlab工具对数据进行预处理,包括图像切片、加权平均、灰度共现矩阵纹理特征提取。然后,在卷积神经网络结构的基础上,引入稀疏交互机制和注意机制,增强特征提取能力和分类性能。使用预处理的MRI图像数据训练ACNet模型,并使用准确度和曲线下面积等指标评估诊断结果和分类准确性。结果在表1中,改进后的模型能有效提高MRI图像的分类准确率和精神分裂症的识别准确率,准确率超过94%,应用效果显著。改进ACNet的MRI图像分类方法,为精神分裂症的计算机辅助诊断提供了新的途径。该模型在特征提取和分类性能上显示出显著的准确率,准确率均超过90%。MRI作为一种无创的脑成像技术,由于能够实现多方向的任意切片,被广泛应用于脑部检查。精神分裂症的核心症状包括幻觉、妄想、思维紊乱和情感冷漠。这些症状通常持续至少6个月,严重影响患者的日常生活和社交功能。MRI在精神分裂症诊断中的应用越来越广泛。在机器学习和深度学习技术的帮助下,MRI图像可以自动分析和分类,以帮助医生做出更准确的诊断。将本研究提出的改进方法应用于MRI图像,可以为疾病的早期干预和精准治疗提供有力支持,有助于更好地了解精神分裂症的神经病理机制,提高患者的生活质量。
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来源期刊
Schizophrenia Bulletin
Schizophrenia Bulletin 医学-精神病学
CiteScore
11.40
自引率
6.10%
发文量
163
审稿时长
4-8 weeks
期刊介绍: Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. We view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. We will give new emphasis to translational reports which simultaneously highlight basic neurobiological mechanisms and clinical manifestations. Some of the Bulletin content is invited as special features or manuscripts organized as a theme by special guest editors. Most pages of the Bulletin are devoted to unsolicited manuscripts of high quality that report original data or where we can provide a special venue for a major study or workshop report. Supplement issues are sometimes provided for manuscripts reporting from a recent conference.
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