{"title":"Later but better peptide modulations","authors":"Guoqing Jin","doi":"10.1038/s41570-025-00696-5","DOIUrl":null,"url":null,"abstract":"A new approach to reshape a set of peptide candidates into stable, drug-like macrocycles has been developed to better target large protein surfaces.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"64 1","pages":""},"PeriodicalIF":38.1000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews. Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1038/s41570-025-00696-5","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A new approach to reshape a set of peptide candidates into stable, drug-like macrocycles has been developed to better target large protein surfaces.
期刊介绍:
Nature Reviews Chemistry is an online-only journal that publishes Reviews, Perspectives, and Comments on various disciplines within chemistry. The Reviews aim to offer balanced and objective analyses of selected topics, providing clear descriptions of relevant scientific literature. The content is designed to be accessible to recent graduates in any chemistry-related discipline while also offering insights for principal investigators and industry-based research scientists. Additionally, Reviews should provide the authors' perspectives on future directions and opinions regarding the major challenges faced by researchers in the field.