107 THE IMPACT OF ENGLISH TEACHING AND LANGUAGE TRAINING ON COGNITIVE FUNCTION IN SCHIZOPHRENIA PATIENTS: AN EMPIRICAL STUDY

IF 4.8 1区 医学 Q1 PSYCHIATRY Schizophrenia Bulletin Pub Date : 2025-02-18 DOI:10.1093/schbul/sbaf007.107
Xinhua Guo, Xiang Zhao*
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Abstract

Background Cognitive deficits are a core feature of schizophrenia, affecting multiple domains such as attention, memory, and executive functions. These impairments significantly contribute to the disability associated with the disorder and can hinder daily functioning and rehabilitation efforts. Recent research has suggested that cognitive remediation therapy, including language training, may improve cognitive outcomes in schizophrenia. However, the extent to which English teaching and language training can enhance cognitive function in schizophrenia patients remains unclear. This study aims to investigate whether English teaching and language training can improve cognitive functions in schizophrenia patients and explore the underlying mechanisms. Methods A total of 300 schizophrenia patients were randomly assigned to either an English teaching and language training group (n=150) or a control group (n=150). The intervention group participated in a 12-week program that included English language instruction and cognitive exercises designed to enhance language skills. The control group received standard care without additional language training. Cognitive function was assessed using the MATRICS Consensus Cognitive Battery (MCCB), which measures six cognitive domains: attention, memory, language, reasoning and problem-solving, social cognition, and motor skills. Pre- and post-intervention assessments were conducted to evaluate changes in cognitive performance. Results Statistical analysis was performed using a mixed-design ANOVA with group (intervention vs. control) as the between-subjects factor and time (pre- vs. post-intervention) as the within-subjects factor. Results showed a significant interaction effect for language (F (1, 298) = 4.56, P = 0.034, η² = 0.015) and reasoning and problem-solving (F (1, 298) = 5.21, P = 0.023, η² = 0.017). Post-hoc tests revealed that the intervention group demonstrated significant improvements in language (P = 0.012, d = 0.68) and reasoning and problem-solving (P = 0.011, d = 0.71) compared to the control group. No significant differences were observed in the other cognitive domains. Additionally, a correlation analysis indicated a moderate positive correlation between language improvement and social cognition (r = 0.45, P < 0.001), suggesting that language training may have broader cognitive benefits. Discussion The research results indicate that English teaching and language training have a significant improvement effect on specific cognitive domains of patients with schizophrenia, especially in language and reasoning problem-solving abilities. The intervention group showed a moderate improvement in the language domain with an effect size of 0.68 and in the reasoning problem-solving domain with an effect size of 0.71. This discovery supports the potential value of incorporating language training into cognitive correction therapy. Future research should further explore the long-term effects of language training on improving patients’ cognitive function, as well as how to translate these training effects into practical applications in daily life, in order to more comprehensively evaluate its contribution to patients’ social function recovery. Meanwhile, the study also found a positive correlation between language training and social cognition, suggesting that language training may have a positive effect on improving patients’ social skills, which is worth further exploration in future research.
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英语教学与语言训练对精神分裂症患者认知功能影响的实证研究
认知缺陷是精神分裂症的一个核心特征,影响注意力、记忆和执行功能等多个领域。这些损伤显著地导致了与疾病相关的残疾,并可能阻碍日常功能和康复努力。最近的研究表明,包括语言训练在内的认知补救疗法可能会改善精神分裂症患者的认知结果。然而,英语教学和语言训练能在多大程度上提高精神分裂症患者的认知功能仍不清楚。本研究旨在探讨英语教学和语言训练是否能改善精神分裂症患者的认知功能,并探讨其机制。方法将300例精神分裂症患者随机分为英语教学和语言训练组(n=150)和对照组(n=150)。干预组参加了一个为期12周的项目,包括英语语言教学和旨在提高语言技能的认知练习。对照组接受标准治疗,没有额外的语言训练。认知功能的评估使用了matrix共识认知电池(MCCB),它测量了六个认知领域:注意力、记忆、语言、推理和解决问题、社会认知和运动技能。进行干预前和干预后的评估,以评估认知表现的变化。结果采用混合设计方差分析进行统计分析,以组(干预与对照组)为受试者间因素,时间(干预前与干预后)为受试者内因素。结果显示,在语言(F (1,298) = 4.56, P = 0.034, η²= 0.015)和推理和解决问题(F (1,298) = 5.21, P = 0.023, η²= 0.017)方面存在显著的交互作用。事后测试显示,与对照组相比,干预组在语言(P = 0.012, d = 0.68)和推理和解决问题(P = 0.011, d = 0.71)方面表现出显著的改善。在其他认知领域没有观察到显著差异。此外,相关分析显示语言进步与社会认知之间存在中度正相关(r = 0.45, P <;0.001),这表明语言训练可能有更广泛的认知益处。研究结果表明,英语教学和语言训练对精神分裂症患者的特定认知领域有显著的改善作用,尤其是在语言和推理问题解决能力方面。干预组在语言领域有中等程度的改善,效应量为0.68,在推理问题解决领域有中等程度的改善,效应量为0.71。这一发现支持了将语言训练纳入认知矫正疗法的潜在价值。未来的研究应进一步探索语言训练对患者认知功能改善的长期效果,以及如何将这些训练效果转化为日常生活中的实际应用,以更全面地评估其对患者社会功能恢复的贡献。同时,本研究还发现语言训练与社会认知之间存在正相关关系,提示语言训练可能对提高患者的社交技能有积极作用,值得在未来的研究中进一步探索。
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来源期刊
Schizophrenia Bulletin
Schizophrenia Bulletin 医学-精神病学
CiteScore
11.40
自引率
6.10%
发文量
163
审稿时长
4-8 weeks
期刊介绍: Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. We view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. We will give new emphasis to translational reports which simultaneously highlight basic neurobiological mechanisms and clinical manifestations. Some of the Bulletin content is invited as special features or manuscripts organized as a theme by special guest editors. Most pages of the Bulletin are devoted to unsolicited manuscripts of high quality that report original data or where we can provide a special venue for a major study or workshop report. Supplement issues are sometimes provided for manuscripts reporting from a recent conference.
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