{"title":"Molecular Imaging of Ovarian Follicles and Tumors With Near-Infrared II Bioconjugates (Adv. Mater. 7/2025)","authors":"Yicong Wang, Wenhan Lu, Zi-Han Chen, Yan Xiao, Yu Wang, Wenhao Gao, Zhiming Wang, Ruihu Song, Zhao Fang, Wei Hu, Xiaoyu Tong, Kuinyu Lee, Zhenle Pei, Minzhen Xu, Fan Zhang, Hao Chen, Yi Feng","doi":"10.1002/adma.202570058","DOIUrl":null,"url":null,"abstract":"<p><b>Molecular Imaging</b></p><p>Monitoring follicular development is crucial for evaluating female fertility and diagnosing infertility. This work introduces a novel NIR-II imaging strategy using FDA-approved ICG-conjugated hCG protein, enabling high-resolution, long-term tracking of early follicles. Beyond infertility diagnosis, this method also identifies ovarian tumors and micro-metastases, offering a groundbreaking tool for reproductive and oncological applications. More details can be found in article number 2414129 by Hao Chen, Yi Feng, and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 7","pages":""},"PeriodicalIF":27.4000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570058","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Materials","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adma.202570058","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Molecular Imaging
Monitoring follicular development is crucial for evaluating female fertility and diagnosing infertility. This work introduces a novel NIR-II imaging strategy using FDA-approved ICG-conjugated hCG protein, enabling high-resolution, long-term tracking of early follicles. Beyond infertility diagnosis, this method also identifies ovarian tumors and micro-metastases, offering a groundbreaking tool for reproductive and oncological applications. More details can be found in article number 2414129 by Hao Chen, Yi Feng, and co-workers.
期刊介绍:
Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.