Asymptomatic testing people for SARS-CoV-2 in healthcare facilities: A systematic review.

IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Public Health in Africa Pub Date : 2025-01-03 eCollection Date: 2025-01-01 DOI:10.4102/jphia.v16i2.581
Olabisi A Oduwole, Glory Bassey, Grace Esebanmen, Samuel Shoyinka, Johnsolomon Ohenhen, Elise Cogo, Nicholas Henschke, Eleanor Ochodo, Martin M Meremikwu
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Abstract

Background: Asymptomatic testing involves the process whereby individuals who do not show symptoms of COVID-19 are tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using any of the available laboratory test techniques.

Aim: To evaluate the effectiveness of testing asymptomatic individuals visiting, living or working in healthcare facilities in reducing SARS-CoV-2 viral infections.

Setting: Healthcare databases.

Method: Electronic databases were searched and limited to English language and studies published 2020 to 02 September 2022. Following the methods for rapid systematic reviews, data were analysed using a fixed effect model, and results of the effect estimate were reported as odds ratios (OR) with their confidence intervals (CI) (95% CI).

Results: Databases' searches yielded 3065 articles after deduplication and 3 studies by searching reference lists of included articles. After screening abstracts and full text articles, 3 cohort studies were included, each with serious risk of bias. Very low certainty evidence shows a decrease in occurrence of SARS-CoV-2 infections in the asymptomatic testing group among patients going for index surgery (OR: 0.05, 95 % CI: 0.00-0.82; 501 participants; 1 study) and among long term care facility staff (OR: 0.31, 95 % CI: 0.18-0.52; 3457 participants; 2 studies, I 2 = 89%) than the 'no asymptomatic testing' group. However, its effect on their residents was contradictory.

Conclusion: There is limited quality evidence to support asymptomatic testing of individuals for SARS-CoV-2 in the prevention of virus transmission in health care settings.

Contribution: In the event of a future pandemic, this review offers current evidence on the potential effects of asymptomatic testing.

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在医疗机构对无症状人群进行SARS-CoV-2检测:一项系统综述。
背景:无症状检测是指使用任何可用的实验室检测技术对未出现COVID-19症状的个体进行严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)感染检测的过程。目的:评价对在医疗机构就诊、生活或工作的无症状人员进行检测对减少SARS-CoV-2病毒感染的效果。设置:医疗保健数据库。方法:检索电子数据库,仅限于英语和发表于2020年至2022年9月2日的研究。按照快速系统评价的方法,使用固定效应模型分析数据,并以优势比(OR)及其置信区间(95% CI)报告效果估计结果。结果:在数据库中检索到重复数据删除后的文献3065篇,检索到纳入文献的参考文献3篇。在筛选摘要和全文文章后,纳入了3项队列研究,每项研究都有严重的偏倚风险。极低确定性证据显示,在无症状检测组接受指数手术的患者中,SARS-CoV-2感染发生率下降(OR: 0.05, 95% CI: 0.00-0.82;501名参与者;1项研究)和长期护理机构工作人员(OR: 0.31, 95% CI: 0.18-0.52;3457名参与者;2项研究,I 2 = 89%)比“无无症状检测”组少。然而,它对居民的影响是矛盾的。结论:支持在卫生保健机构对个体进行无症状SARS-CoV-2检测以预防病毒传播的证据质量有限。贡献:在未来发生大流行的情况下,本综述提供了关于无症状检测潜在影响的现有证据。
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来源期刊
Journal of Public Health in Africa
Journal of Public Health in Africa PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
自引率
0.00%
发文量
82
审稿时长
10 weeks
期刊介绍: The Journal of Public Health in Africa (JPHiA) is a peer-reviewed, academic journal that focuses on health issues in the African continent. The journal editors seek high quality original articles on public health related issues, reviews, comments and more. The aim of the journal is to move public health discourse from the background to the forefront. The success of Africa’s struggle against disease depends on public health approaches.
期刊最新文献
Charting Africa's digital public health future: Five priorities for action. Traditional health practices in child care: Perceptions of caregivers in a township community. Evaluation of the concordance between nasopharyngeal and oropharyngeal swabs in the detection of COVID-19. Prioritisation and risk ranking of epidemic-prone diseases for emergency preparedness and response in Eastern Africa using a multi-criteria decision analysis framework, 2023. COVID-19 and ethics in action: Insights from African research committees.
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