Highlighting recent achievements to advance more effective cancer immunotherapy.

IF 12.8 1区 医学 Q1 ONCOLOGY Journal of Experimental & Clinical Cancer Research Pub Date : 2025-02-18 DOI:10.1186/s13046-025-03316-8
Beatrice Belmonte, Sheila Spada, Paola Allavena, Matteo Benelli, Vincenzo Bronte, Giulia Casorati, Lorenzo D'Ambrosio, Roberto Ferrara, Anna Mondino, Paola Nisticò, Roberta Sommaggio, Marcella Tazzari, Claudio Tripodo, Antonio Sica, Pier Francesco Ferrucci
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Abstract

From 17 to 19th October 2024, the XXI Italian Network for Bio-Immunotherapy of Tumors Meeting (NIBIT) took place in Palermo, in the marvelous historical location of Teatro Politeama, under the auspices of the Italian Association of Medical Oncology (AIOM), Italian Association of Cancer Research (AIRC), Fondazione Pezcoller, Italian Alliance against Cancer (ACC), Italian Lymphoma Foundation (FIL), Grazia Focacci Foundation and Melagioco Foundation. The conference covered a spectrum of topics ranging from target discovery to therapeutic advances in immuno-oncology, bringing world-renowned experts to present groundbreaking innovations in basic, translational, and clinical cancer research. Six sessions focused on cellular therapies, digital pathology, vaccines, tertiary lymphoid structures, and microenvironment in order to get deep insights on how to personalize diagnosis and therapies in the clinical setting. Young investigators had the opportunity to meet and greet their mentors, promoting the synergy of the academic and industrial sectors within the national and international panorama, discussing the application of artificial intelligence on multi-specific antibodies, drug conjugates, and antibody fusion proteins that are advancing the efficacy of precision medicine and minimizing off-target effects.

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强调最近取得的进展,以促进更有效的癌症免疫治疗。
2024年10月17日至19日,在意大利肿瘤医学协会(AIOM)、意大利癌症研究协会(AIRC)、基金会Pezcoller、意大利抗癌联盟(ACC)、意大利淋巴瘤基金会(FIL)、Grazia Focacci基金会和Melagioco基金会的赞助下,第21届意大利肿瘤生物免疫治疗网络会议(NIBIT)在巴勒莫的Politeama剧院举行。会议涵盖了从目标发现到免疫肿瘤学治疗进展的一系列主题,汇集了世界知名专家,介绍了基础,转化和临床癌症研究方面的突破性创新。六场会议聚焦于细胞治疗、数字病理学、疫苗、三级淋巴结构和微环境,以深入了解如何在临床环境中个性化诊断和治疗。年轻的研究人员有机会与他们的导师见面,在国内和国际的视野中促进学术和工业部门的协同作用,讨论人工智能在多特异性抗体、药物偶联物和抗体融合蛋白方面的应用,这些应用正在提高精准医学的功效,并最大限度地减少脱靶效应。
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来源期刊
CiteScore
18.20
自引率
1.80%
发文量
333
审稿时长
1 months
期刊介绍: The Journal of Experimental & Clinical Cancer Research is an esteemed peer-reviewed publication that focuses on cancer research, encompassing everything from fundamental discoveries to practical applications. We welcome submissions that showcase groundbreaking advancements in the field of cancer research, especially those that bridge the gap between laboratory findings and clinical implementation. Our goal is to foster a deeper understanding of cancer, improve prevention and detection strategies, facilitate accurate diagnosis, and enhance treatment options. We are particularly interested in manuscripts that shed light on the mechanisms behind the development and progression of cancer, including metastasis. Additionally, we encourage submissions that explore molecular alterations or biomarkers that can help predict the efficacy of different treatments or identify drug resistance. Translational research related to targeted therapies, personalized medicine, tumor immunotherapy, and innovative approaches applicable to clinical investigations are also of great interest to us. We provide a platform for the dissemination of large-scale molecular characterizations of human tumors and encourage researchers to share their insights, discoveries, and methodologies with the wider scientific community. By publishing high-quality research articles, reviews, and commentaries, the Journal of Experimental & Clinical Cancer Research strives to contribute to the continuous improvement of cancer care and make a meaningful impact on patients' lives.
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