Association between Nurse Continuity and Mortality in the Intensive Care Unit.

Kathryn A Connell, Billie S Davis, Jeremy M Kahn
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Abstract

Rationale: Continuity of nursing care is highly valued in the intensive care unit (ICU), but its impact on patient outcomes remains unclear. Objectives: To investigate the relationship between nurse continuity and mortality among ICU patients. Methods: We performed a retrospective cohort study using electronic health records from 38 ICUs across 18 hospitals between 2018 and 2020. Cumulative nurse continuity was defined at the shift level as the proportion of 12-hour shifts in which the patient received care from a nurse who had previously provided care to them, up to and including the present shift. Employing a landmark analysis framework, we used logistic regression to assess the relationship between in-hospital mortality and cumulative nurse continuity at each shift, adjusting for potential confounders. Results: The study included 47,564 ICU patients. In-hospital mortality was 10.4%. Average cumulative nurse continuity increased from 10.2% at shift 3 to 34.2% at shift 14. In the regression models, increasing cumulative nurse continuity was associated with a modest but statistically significant increase in mortality in some but not all shifts. The results were robust to sensitivity analyses, including limiting the cohort to patients receiving mechanical ventilation, excluding patients admitted during the COVID-19 pandemic, using different measures of continuity, and treating continuity as a time-varying covariate using proportional hazards regression. Conclusions: Nurse continuity was not associated with lower mortality and may lead to increased mortality in some settings. Further research is needed to understand the mechanisms underlying the association between nurse continuity and ICU outcomes.

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重症监护室护士护理连续性与死亡率之间的关系。
理由:在重症监护室(ICU),护理的连续性受到高度重视,但其对患者预后的影响尚不清楚。目的:探讨护士连续性与ICU患者死亡率的关系。方法:我们对2018年至2020年间18家医院38个icu的电子健康记录进行了回顾性队列研究。累计护士连续性在轮班水平上被定义为患者从以前提供护理的护士那里接受护理的12小时轮班的比例,直至并包括当前轮班。采用里程碑式分析框架,我们使用逻辑回归来评估住院死亡率与每班累积护士连续性之间的关系,并对潜在的混杂因素进行调整。测量方法及主要结果:纳入47,564例ICU患者。住院死亡率为10.4%。护士的平均累积连续性从3班的10.2%增加到14班的34.2%。在回归模型中,增加护士的累积连续性与一些班次(但不是所有班次)的死亡率有适度但统计上显著的增加有关。结果对敏感性分析具有稳健性,包括将队列限制为接受机械通气的患者,排除COVID-19大流行期间入院的患者,使用不同的连续性措施,并使用比例风险回归将连续性视为时变协变量。结论:护士连续性与较低的死亡率无关,在某些情况下可能导致死亡率增加。需要进一步的研究来了解护士连续性和ICU预后之间的关联机制。
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