{"title":"Une modification des trajectoires est-elle possible ? Stratégies et perspectives","authors":"P. Eigenmann","doi":"10.1016/j.reval.2024.104223","DOIUrl":null,"url":null,"abstract":"<div><div>Allergy represents a class of diseases with a time-specific trajectory, as well as an interweaving suggesting either comorbidities or multimorbidities. Our knowledge of allergic diseases and their trajectories has increased significantly through the study of prospective cohorts of patients. It is currently known that this dynamic process is influenced by various factors, especially environmental ones, that interact with the individual, his immune system, while challenging the permeability of the barriers between the environment and the immune system. The management of allergy involves knowledge of the trajectories of the various pathologies, using available therapeutic options for modulation of allergic inflammation aiming for optimal tolerance.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 ","pages":"Article 104223"},"PeriodicalIF":0.3000,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue Francaise d Allergologie","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1877032024004445","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Allergy represents a class of diseases with a time-specific trajectory, as well as an interweaving suggesting either comorbidities or multimorbidities. Our knowledge of allergic diseases and their trajectories has increased significantly through the study of prospective cohorts of patients. It is currently known that this dynamic process is influenced by various factors, especially environmental ones, that interact with the individual, his immune system, while challenging the permeability of the barriers between the environment and the immune system. The management of allergy involves knowledge of the trajectories of the various pathologies, using available therapeutic options for modulation of allergic inflammation aiming for optimal tolerance.
期刊介绍:
La Revue Française d''Allergologie : un véritable forum pour faire connaître des travaux originaux et permettre la diffusion de l''information auprès de toutes les spécialités concernées par les pathologies allergiques. La Revue Française d''Allergologie (8 numéros par an) est au carrefour de nombreuses spécialités - dermatologie, pédiatrie, ORL, pneumologie, ophtalmologie, médecine interne - qui, toutes, ont à traiter des maladies allergiques. Les symptômes des allergies fondés sur des mécanismes communs sont le plus souvent associés et se succèdent chez un même patient. En forte progression depuis 20 ans, les maladies allergiques sont dans l''attente de perfectionnements et d''avancées thérapeutiques qui permettront aux nombreux patients qui en sont atteints de mieux vivre avec leurs allergies. La Revue Française d''Allergologie se veut donc un véritable forum de discussions et d''échanges entre tous les spécialistes confrontés aux pathologies