Evaluation of Heavy Menstrual Bleeding in Adolescents

IF 1.5 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Journal of Clinical Research in Pediatric Endocrinology Pub Date : 2025-12-11 Epub Date: 2025-02-20 DOI:10.4274/jcrpe.galenos.2025.2024-11-19
Tuğba Kontbay Çetin, Zuhal Keskin Sarılar
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Abstract

Objective: Heavy menstrual bleeding (HMB) in adolescents often manifests as “excessive bleeding” and may result in acute anemia requiring emergency treatment. The aim of this study was to evaluate the diagnostic and management options for adolescents with HMB.

Methods: Retrospective data were collected from patients’ medical records. Adolescents were classified based on the degree of anemia: Group 1 included patients with hemoglobin (Hb) levels of <8 g/dL; Group 2, Hb levels of 8-10 g/dL; Group 3, Hb levels of 10-12 g/dL; and Group 4, Hb levels of ≥12 g/dL. Admission and follow-up characteristics were compared across groups.

Results: The cohort consisted of 122 adolescents with a mean age of 13.7±1.9 years, 42.7% of whom experienced menstrual irregularity within two years of menarche. The median duration of bleeding was 16 (10-30) days. Anovulation was identified in 57.8% of patients. Polycystic ovary syndrome was diagnosed in 32 (25%) adolescents, hypothyroidism in 6 (4.7%), uterine structural anomalies in 3 (2.3%), and hyperprolactinemia in 3 (2.3%), 2 of whom had microprolactinoma. One adolescent was diagnosed with von Willebrand disease following a hematological evaluation.

Conclusion: Primary care providers should understand normal menstrual cycle patterns and thus be adept at identifying HMB. Early recognition of the underlying etiology in adolescents facilitates timely diagnosis, helping to prevent severe anemia and potential hospitalization.

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评估青少年月经过多。
目的:青少年大量月经出血(HMB)常表现为“出血过多”,可能导致急性贫血,需要紧急治疗。本研究旨在评估青少年HMB的诊断和治疗方案。方法:回顾性收集患者病历资料。根据贫血程度对青少年进行分类:第一组包括血红蛋白(Hb)水平的患者。结果:该队列包括122名青少年,平均年龄为13.7±1.9岁,其中42.7%的人在月经初潮后2年内出现月经不调。平均出血时间16天(范围:10 ~ 30天)。57.8%的患者无排卵。青少年多囊卵巢综合征32例(25%),甲状腺功能减退6例(4.7%),子宫结构异常3例(2.3%),高泌乳素血症3例(2.3%),其中2例有微泌乳素瘤。一名青少年在血液学评估后被诊断患有血管性血友病。结论:初级保健提供者必须了解正常的月经周期模式,并善于识别HMB。早期识别青少年的潜在病因有助于及时诊断,有助于预防严重贫血和住院治疗。
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来源期刊
Journal of Clinical Research in Pediatric Endocrinology
Journal of Clinical Research in Pediatric Endocrinology ENDOCRINOLOGY & METABOLISM-PEDIATRICS
CiteScore
3.60
自引率
5.30%
发文量
73
审稿时长
20 weeks
期刊介绍: The Journal of Clinical Research in Pediatric Endocrinology (JCRPE) publishes original research articles, reviews, short communications, letters, case reports and other special features related to the field of pediatric endocrinology. JCRPE is published in English by the Turkish Pediatric Endocrinology and Diabetes Society quarterly (March, June, September, December). The target audience is physicians, researchers and other healthcare professionals in all areas of pediatric endocrinology.
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