Compartmentalization of multilayer microreactors using protein-polymer hybrids

IF 4.1 2区 化学 Q2 POLYMER SCIENCE Polymer Pub Date : 2025-02-21 DOI:10.1016/j.polymer.2025.128182
Irene Alonso-Sampedro, Aitor Larrañaga, Ana Beloqui
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Abstract

The application of a layer-by-layer approach for stabilizing inorganic particles, such as calcium carbonate, with polyelectrolytes leads to the formation of core-shell architectures that create distinct environments for protein confinement. In this study, we propose embedding enzymes within the polymeric shell by synthesizing polymer-enzyme hybrids. These hybrids are designed to be effectively entrapped among the polymer layers through electrostatic interactions. Consequently, we have investigated the localization of enzymes within the various confinements provided by layered particles and evaluated their potential to function as catalytic microreactors.

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来源期刊
Polymer
Polymer 化学-高分子科学
CiteScore
7.90
自引率
8.70%
发文量
959
审稿时长
32 days
期刊介绍: Polymer is an interdisciplinary journal dedicated to publishing innovative and significant advances in Polymer Physics, Chemistry and Technology. We welcome submissions on polymer hybrids, nanocomposites, characterisation and self-assembly. Polymer also publishes work on the technological application of polymers in energy and optoelectronics. The main scope is covered but not limited to the following core areas: Polymer Materials Nanocomposites and hybrid nanomaterials Polymer blends, films, fibres, networks and porous materials Physical Characterization Characterisation, modelling and simulation* of molecular and materials properties in bulk, solution, and thin films Polymer Engineering Advanced multiscale processing methods Polymer Synthesis, Modification and Self-assembly Including designer polymer architectures, mechanisms and kinetics, and supramolecular polymerization Technological Applications Polymers for energy generation and storage Polymer membranes for separation technology Polymers for opto- and microelectronics.
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