The absolute volume of Gleason Pattern 4 on radical prostatectomy is more strongly associated with advanced stage and biochemical recurrence than Gleason grade groups.
Simone Scuderi, Amy L Tin, Jared Klug, Shaun Porwal, Leonardo Quarta, Margherita Ciabattini, Nazario Pio Tenace, Riccardo Leni, Roberta Lucianò, Armando Stabile, Giorgio Gandaglia, James A Eastham, Francesco Montorsi, Alberto Briganti, Andrew J Vickers
{"title":"The absolute volume of Gleason Pattern 4 on radical prostatectomy is more strongly associated with advanced stage and biochemical recurrence than Gleason grade groups.","authors":"Simone Scuderi, Amy L Tin, Jared Klug, Shaun Porwal, Leonardo Quarta, Margherita Ciabattini, Nazario Pio Tenace, Riccardo Leni, Roberta Lucianò, Armando Stabile, Giorgio Gandaglia, James A Eastham, Francesco Montorsi, Alberto Briganti, Andrew J Vickers","doi":"10.1097/ju.0000000000004484","DOIUrl":null,"url":null,"abstract":"ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume is more strongly associated with advanced stage and biochemical recurrence than GG in patients with pattern 4 but not 5.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"20 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ju.0000000000004484","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume is more strongly associated with advanced stage and biochemical recurrence than GG in patients with pattern 4 but not 5.