Cortical activation and functional connectivity in visual-cognitive-motor networks during motor-cognitive exercise

Abstract

Purpose

When compared to computer-based brain training, motor-cognitive exercises and exergaming claim to provide stronger brain activation and better transfer due to the integration of a more complex motor task. To evaluate if this is supported by neural dynamics, this study compared event-related potentials and connectivity between a cognitive and motor-cognitive training task.

Methods

21 participants performed a choice-reaction task with either an upper extremity button press (cognitive condition) or lower extremity stepping movement (motor-cognitive condition) input using the SKILLCOURT technology. The visual stimulation and cognitive task were identical. In addition to reaction time, neural activity was recorded using a 64-channel EEG system. Time course of neural activation and event-related potential data in visual premotor, primary motor and sensory regions of interest were compared between conditions. In addition, connectivity was calculated to identify differences in functional communication.

Results

Neural engagement was stronger in the motor-cognitive condition as reflected by a higher amplitude (p < 0.001) and longer latency (p = 0.02) of the BA6 negativity potential as well as higher activity in electrodes representing the foot region of the primary motor cortex (p < 0.001). This was accompanied by enhanced connectivity between electrodes covering the premotor cortex and frontal, primary motor and visual areas p < 0.05).

Conclusion

The findings suggest that the premotor cortex plays a key role in motor-cognitive training. This supports the assumption of stronger engagement of motor areas in motor-cognitive when compared to cognitive training and shed light on the neural processes that may underly superior training effects when compared to computer-based cognitive training.