Early vaccine effectiveness estimates against medically attended laboratory-confirmed influenza based on influenza surveillance, Beijing, China, 2024/25 season.

IF 7.8 2区 医学 Q1 INFECTIOUS DISEASES Eurosurveillance Pub Date : 2025-02-01 DOI:10.2807/1560-7917.ES.2025.30.7.2500084
Ying Sun, Weixian Shi, Daitao Zhang, Chunna Ma, Zhaomin Feng, Jiaojiao Zhang, Dan Wu, Li Zhang, Jia Li, Wei Duan, Yingying Wang, Jiaxin Ma, Lu Zhang, Xiaodi Hu, Peng Yang, Quanyi Wang
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Abstract

We estimated early influenza vaccine effectiveness (VE) for the 2024/25 season in outpatients, in Beijing using a test-negative design. A(H1N1)pdm09 dominated (99.3%), all sequenced strains (n = 38) clustered in clade 6B.1A.5a.2a, and 37 of 38 antigenically similar to the vaccine strain. VE against any influenza virus infection was 48.5% (95% CI: 34.8-59.5) and 48.7% (95% CI: 35.1-59.7) against A(H1N1)pdm09. Vaccination in the current or previous season against any influenza showed a VE of 52.5% to 54.9%, compared to no vaccination in both seasons.

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基于流感监测的针对医务人员在场实验室确诊流感的早期疫苗有效性估计,中国北京,2024/25季节
我们采用检测阴性设计估算了北京门诊患者在2024/25季节的早期流感疫苗有效性(VE)。A(H1N1)pdm09型占多数(99.3%),所有测序株(n = 38)聚集在6B.1A.5a支系。38株中有37株的抗原性与疫苗株相似。对流感病毒感染的VE为48.5%(95% CI: 34.8-59.5),对甲型H1N1流感病毒pdm09的VE为48.7%(95% CI: 35.1-59.7)。与两个季节均未接种疫苗相比,在当前或上一个季节接种任何流感疫苗的VE为52.5%至54.9%。
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来源期刊
Eurosurveillance
Eurosurveillance INFECTIOUS DISEASES-
CiteScore
32.70
自引率
2.10%
发文量
430
审稿时长
3-8 weeks
期刊介绍: Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.
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