Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care - a pilot study.

IF 3.2 3区 医学 Q2 PSYCHIATRY Frontiers in Psychiatry Pub Date : 2025-02-06 eCollection Date: 2025-01-01 DOI:10.3389/fpsyt.2025.1473988
Anna Persson, Daniel Wallhed Finn, Alice Broberg, Amanda Westerberg, Åsa Magnusson, Olof Molander
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Abstract

Introduction: Major depression and alcohol use disorder affect millions of individuals worldwide and cause significant disability. They often occur together, and their co-occurrence is associated with more negative outcomes than each disorder on its own. Yet, there is a lack of knowledge on how to best treat co-occurring depression and alcohol use disorder. A pilot study was conducted to investigate the feasibility, credibility, patient satisfaction, preliminary effect, and potential negative effects of an integrated treatment for depression and alcohol use disorder, which has shown promising results in an earlier pilot trial.

Methods: The study was conducted at an outpatient unit in Stockholm, Sweden. Women (n=7) with current depression and alcohol use disorder were offered integrated group treatment that included evidence-based treatment for depression and alcohol use disorder. Criteria for feasibility were based on an earlier study, treatment credibility was measured using the Credibility/Expectancy Questionnaire and patient satisfaction with the Client Satisfaction Questionnaire.

Results: Feasibility, credibility, and patient satisfaction were high. Depression symptom severity and alcohol consumption decreased from baseline to follow up. Negative effects were reported in terms of increased adverse emotional experiences.

Discussion: The investigated integrated treatment for co-occurring depression and alcohol use disorder continues to show promise. Randomized clinical trials are needed to evaluate its effectiveness.

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女性抑郁症和中重度酒精使用障碍的综合治疗在常规酒精使用障碍护理中大有可为--一项试点研究。
重度抑郁症和酒精使用障碍影响着全世界数百万人,并导致严重的残疾。它们经常一起发生,它们的共同出现比单独出现的疾病带来更多的负面结果。然而,对于如何最好地治疗同时发生的抑郁症和酒精使用障碍,人们缺乏知识。进行了一项试点研究,以调查抑郁症和酒精使用障碍综合治疗的可行性、可信度、患者满意度、初步效果和潜在负面影响,该研究在早期的试点试验中显示出有希望的结果。方法:该研究在瑞典斯德哥尔摩的一家门诊进行。目前患有抑郁症和酒精使用障碍的妇女(n=7)接受综合小组治疗,包括对抑郁症和酒精使用障碍的循证治疗。可行性标准基于早期的研究,治疗可信性使用可信性/期望问卷和患者满意度客户满意度问卷进行测量。结果:本方法具有较高的可行性、可信性和患者满意度。抑郁症状严重程度和酒精摄入量从基线到随访均有所下降。据报道,负面影响表现为不良情绪体验的增加。讨论:对同时发生的抑郁症和酒精使用障碍的综合治疗的调查继续显示出希望。需要随机临床试验来评估其有效性。
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来源期刊
Frontiers in Psychiatry
Frontiers in Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
6.20
自引率
8.50%
发文量
2813
审稿时长
14 weeks
期刊介绍: Frontiers in Psychiatry publishes rigorously peer-reviewed research across a wide spectrum of translational, basic and clinical research. Field Chief Editor Stefan Borgwardt at the University of Basel is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. The journal''s mission is to use translational approaches to improve therapeutic options for mental illness and consequently to improve patient treatment outcomes.
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