The impact of blood on vector-borne diseases with emphasis on mosquitoes and sand flies.

IF 6.6 1区 医学 Q1 PARASITOLOGY Trends in parasitology Pub Date : 2025-03-01 Epub Date: 2025-02-19 DOI:10.1016/j.pt.2025.01.009
Pedro Cecilio, Eva Iniguez, Patrick Huffcutt, Servio P Ribeiro, Shaden Kamhawi, Jesus G Valenzuela, Tiago D Serafim
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Abstract

The impact of blood and its factors on vector-borne diseases is significant and multifaceted yet understudied. While blood is expected to play a central role in transmission, pathogen development, vector behavior, and vector competence, in experimental settings, most studies are developed in the frame of a single, infected blood meal. To effectively combat vector-borne diseases, we need to determine what is the influence of insect blood-feeding behavior on transmission and development of pathogens, toward translation to natural field settings. This review summarizes current findings, highlights key gaps, and outlines future research directions to enhance our understanding of the role of blood in vector-borne disease transmission.

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血液对媒介传播疾病的影响,重点是蚊子和沙蝇。
血液及其因素对媒介传播疾病的影响是重要的和多方面的,但尚未得到充分研究。虽然预计血液在传播、病原体发展、病媒行为和病媒能力方面发挥核心作用,但在实验环境中,大多数研究都是在单一受感染血液的框架内开展的。为了有效地对抗媒介传播的疾病,我们需要确定昆虫吸血行为对病原体传播和发展的影响,并将其转化为自然野外环境。这篇综述总结了目前的发现,突出了关键的差距,并概述了未来的研究方向,以加强我们对血液在媒介传播疾病传播中的作用的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Trends in parasitology
Trends in parasitology 医学-寄生虫学
CiteScore
14.00
自引率
3.10%
发文量
148
审稿时长
6-12 weeks
期刊介绍: Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.
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