Primary chondrosarcoma of the ovary

IF 1.5 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Journal of Obstetrics and Gynaecology Research Pub Date : 2025-02-23 DOI:10.1111/jog.16250
Yukiko Matsuzawa, Hiroki Kurosawa, Kazuhiro Murakami, Mitsumasa Osakabe, Yoh Watanabe
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Abstract

Ovarian heterologous sarcoma is a rare malignancy. Only three cases of ovarian chondrosarcoma have been reported in the literature, and almost all of these were components of ovarian teratomas. Herein, we report the clinicopathological characteristics of an ovarian chondrosarcoma in a 68-year-old woman who had previously undergone total hysterectomy. She had no subjective symptoms, and the tumor was unexpectedly found by further examination of osteoarthritis of the hip joint. Preoperative magnetic resonance imaging revealed curious findings of a lobulated high-intensity component with a leaf-vein-like low-intensity component. Computed tomography revealed irregularly distributed ossification extending to the entire tumor. Preoperative levels of CA125, CA19-9, carcinoembryonic antigen, α-fetoprotein, and lactic dehydrogenase were all within normal limits. Macroscopic findings of the surgically resected tumor and pathologic findings revealed no teratoma component in the tumor. Finally, we diagnosed the tumor as a primary chondrosarcoma of the ovary.

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卵巢原发性软骨肉瘤
卵巢异源肉瘤是一种罕见的恶性肿瘤。文献中仅报道了三例卵巢软骨肉瘤,几乎所有这些都是卵巢畸胎瘤的组成部分。在此,我们报告的临床病理特征卵巢软骨肉瘤在一个68岁的妇女谁曾接受全子宫切除术。她没有主观症状,在进一步检查髋关节骨关节炎时意外发现肿瘤。术前磁共振成像显示奇怪的发现分叶状高强度成分与叶脉样低强度成分。计算机断层扫描显示不规则分布的骨化延伸到整个肿瘤。术前CA125、CA19-9、癌胚抗原、α-胎蛋白、乳酸脱氢酶均在正常范围内。手术切除肿瘤的肉眼检查和病理检查显示肿瘤中没有畸胎瘤成分。最后,我们诊断肿瘤为原发性卵巢软骨肉瘤。
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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
376
审稿时长
3-6 weeks
期刊介绍: The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.
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