Case Report: Intradural gout tophi without systemic gout symptoms.

IF 1.6 4区 医学 Q2 SURGERY Frontiers in Surgery Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI:10.3389/fsurg.2025.1472886
Peidong Qing, Shiming Xie, Chaoqun Feng, Hongda Xu, Shengxin Zhao, Lei Zhang, Haitao Deng, Yehui Wang, Youpeng Hu
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Abstract

Background: Gout is a common disease; however, a gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date.

Case presentation: We report the case of a 70-year-old female who presented with lower back pain, right radicular pain, and numbness in the perineal area. Magnetic resonance imaging and computed tomography scans revealed a calcified intradural lesion at the L3 level. The diagnosis of the lesion was not definitive because the patient had no history of gout or manifestations of systemic gout. Surgical removal of the intradural lesion followed by pathological examination confirmed gouty tophi. The postoperative recovery was good, and the patient experienced substantial relief from pain and numbness.

Conclusion: This is the third documented case of gout tophi occurring within the spinal dura. In a literature review, it was found that none of these three patients with intradural gouty tophi had systemic gout manifestations or hyperuricemia, which is a crucial finding. As it is challenging to diagnose intradural gout, awareness among physicians must be increased to optimize the treatment of, and outcomes for, these patients.

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病例报告:硬膜内痛风痛风无全身痛风症状。
背景:痛风是一种常见病;然而,痛风痛风发生在脊髓硬脑膜是极其罕见的,只有两个病例报告的日期。病例介绍:我们报告的情况下,70岁的女性谁提出下背部疼痛,右侧神经根性疼痛,并在会阴区麻木。磁共振成像和计算机断层扫描显示L3层硬膜内病变钙化。病变的诊断是不确定的,因为病人没有痛风史或系统性痛风的表现。手术切除硬膜内病变后病理检查证实痛风痛风。术后恢复良好,患者从疼痛和麻木中得到了实质性的缓解。结论:这是第三例记录在案的痛风痛风发生在硬脑膜内。文献回顾发现,这3例硬膜内痛风痛风患者均无系统性痛风表现或高尿酸血症,这是一个至关重要的发现。由于硬膜内痛风的诊断具有挑战性,因此必须提高医生的认识,以优化这些患者的治疗和结果。
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来源期刊
Frontiers in Surgery
Frontiers in Surgery Medicine-Surgery
CiteScore
1.90
自引率
11.10%
发文量
1872
审稿时长
12 weeks
期刊介绍: Evidence of surgical interventions go back to prehistoric times. Since then, the field of surgery has developed into a complex array of specialties and procedures, particularly with the advent of microsurgery, lasers and minimally invasive techniques. The advanced skills now required from surgeons has led to ever increasing specialization, though these still share important fundamental principles. Frontiers in Surgery is the umbrella journal representing the publication interests of all surgical specialties. It is divided into several “Specialty Sections” listed below. All these sections have their own Specialty Chief Editor, Editorial Board and homepage, but all articles carry the citation Frontiers in Surgery. Frontiers in Surgery calls upon medical professionals and scientists from all surgical specialties to publish their experimental and clinical studies in this journal. By assembling all surgical specialties, which nonetheless retain their independence, under the common umbrella of Frontiers in Surgery, a powerful publication venue is created. Since there is often overlap and common ground between the different surgical specialties, assembly of all surgical disciplines into a single journal will foster a collaborative dialogue amongst the surgical community. This means that publications, which are also of interest to other surgical specialties, will reach a wider audience and have greater impact. The aim of this multidisciplinary journal is to create a discussion and knowledge platform of advances and research findings in surgical practice today to continuously improve clinical management of patients and foster innovation in this field.
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