M4S-Net: a motion-enhanced shape-aware semi-supervised network for echocardiography sequence segmentation.

IF 2.6 4区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Medical & Biological Engineering & Computing Pub Date : 2025-02-24 DOI:10.1007/s11517-025-03330-0
Mingshan Li, Fangyan Tian, Shuyu Liang, Qin Wang, Xianhong Shu, Yi Guo, Yuanyuan Wang
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Abstract

Sequence segmentation of echocardiograms is of great significance for the diagnosis and treatment of cardiovascular diseases. However, the low quality of ultrasound imaging and the complexity of cardiac motion pose great challenges to it. In addition, the difficulty and cost of labeling echocardiography sequences limit the performance of supervised learning methods. In this paper, we proposed a Motion-enhanced Shape-aware Semi-supervised Sequence Segmentation Network named M4S-Net. First, multi-level shape priors are used to enhance the model's shape representation capabilities, overcoming the low image quality and improving single-frame segmentation. Then, a motion-enhanced optimization module utilizes optical flows to assist segmentation in a geometric sense, which robustly responds to the complex motions and ensures the temporal consistency of sequence segmentation. A hybrid loss function is devised to maximize the effectiveness of each module and further improve the temporal stability of predicted masks. Furthermore, the parameter-sharing strategy allows it to perform sequence segmentation in a semi-supervised manner. Massive experiments on both public and in-house datasets show that M4S-Net outperforms the state-of-the-art methods in both spatial and temporal segmentation performance. A downstream apical rocking recognition task based on M4S-Net also achieves an AUC of 0.944, which significantly exceeds specialized physicians.

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M4S-Net:用于超声心动图序列分割的运动增强形状感知半监督网络。
超声心动图序列分割对心血管疾病的诊断和治疗具有重要意义。然而,超声成像的低质量和心脏运动的复杂性给它带来了很大的挑战。此外,标记超声心动图序列的难度和成本限制了监督学习方法的性能。本文提出了一种运动增强的形状感知半监督序列分割网络M4S-Net。首先,利用多级形状先验增强模型的形状表示能力,克服图像质量低的问题,改善单帧分割;然后,运动增强优化模块利用光流在几何意义上辅助分割,以鲁棒响应复杂的运动,并确保序列分割的时间一致性。设计了一种混合损失函数,以最大限度地提高每个模块的有效性,并进一步提高预测掩模的时间稳定性。此外,参数共享策略允许它以半监督的方式进行序列分割。在公共和内部数据集上进行的大量实验表明,M4S-Net在空间和时间分割性能方面都优于最先进的方法。基于M4S-Net的下游根尖晃动识别任务的AUC也达到了0.944,明显超过专科医生。
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来源期刊
Medical & Biological Engineering & Computing
Medical & Biological Engineering & Computing 医学-工程:生物医学
CiteScore
6.00
自引率
3.10%
发文量
249
审稿时长
3.5 months
期刊介绍: Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE).
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