Intracranial Aneurysm Segmentation with a Dual-Path Fusion Network.

IF 3.7 3区 医学 Q2 ENGINEERING, BIOMEDICAL Bioengineering Pub Date : 2025-02-15 DOI:10.3390/bioengineering12020185
Ke Wang, Yong Zhang, Bin Fang
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Abstract

Intracranial aneurysms (IAs), a significant medical concern due to their prevalence and life-threatening nature, pose challenges regarding diagnosis owing to their diminutive and variable morphology. There are currently challenges surrounding automating the segmentation of IAs, which is essential for diagnostic precision. Existing deep learning methods in IAs segmentation tend to emphasize semantic features at the expense of detailed information, potentially compromising segmentation quality. Our research introduces the innovative Dual-Path Fusion Network (DPF-Net), an advanced deep learning architecture crafted to refine IAs segmentation by adeptly incorporating detailed information. DPF-Net, with its unique resolution-preserving detail branch, ensures minimal loss of detail during feature extraction, while its cross-fusion module effectively promotes the connection of semantic information and finer detail features, enhancing segmentation precision. The network also integrates a detail aggregation module for effective fusion of multi-scale detail features. A view fusion strategy is employed to address spatial disruptions in patch generation, thereby improving feature extraction efficiency. Evaluated on the CADA dataset, DPF-Net achieves a remarkable mean Dice similarity coefficient (DSC) of 0.8967, highlighting its potential in automated IAs diagnosis in clinical settings. Furthermore, DPF-Net's outstanding performance on the BraTS 2020 MRI dataset for brain tumor segmentation with a mean DSC of 0.8535 further confirms its robustness and generalizability.

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利用双路径融合网络进行颅内动脉瘤分割
颅内动脉瘤(IAs)由于其普遍性和危及生命的性质而成为一个重要的医学问题,由于其微小和多变的形态,对诊断提出了挑战。目前,在IAs的自动分割方面存在挑战,这对诊断精度至关重要。在IAs分割中,现有的深度学习方法往往以牺牲详细信息为代价来强调语义特征,这可能会影响分割质量。我们的研究引入了创新的双路径融合网络(DPF-Net),这是一种先进的深度学习架构,旨在通过熟练地整合详细信息来细化IAs分割。DPF-Net独特的保分辨率细节分支保证了特征提取过程中细节损失最小,交叉融合模块有效促进了语义信息与更精细细节特征的连接,提高了分割精度。该网络还集成了细节聚合模块,可有效融合多尺度细节特征。采用视图融合策略解决斑块生成过程中的空间干扰问题,提高特征提取效率。在CADA数据集上进行评估,DPF-Net的平均Dice相似系数(DSC)为0.8967,突出了其在临床环境中自动诊断IAs的潜力。此外,DPF-Net在BraTS 2020 MRI数据集上的出色表现(平均DSC为0.8535)进一步证实了其鲁棒性和泛化性。
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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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