A Conceptual Framework for Applying Ethical Principles of AI to Medical Practice.

IF 3.7 3区 医学 Q2 ENGINEERING, BIOMEDICAL Bioengineering Pub Date : 2025-02-13 DOI:10.3390/bioengineering12020180
Debesh Jha, Gorkem Durak, Vanshali Sharma, Elif Keles, Vedat Cicek, Zheyuan Zhang, Abhishek Srivastava, Ashish Rauniyar, Desta Haileselassie Hagos, Nikhil Kumar Tomar, Frank H Miller, Ahmet Topcu, Anis Yazidi, Jan Erik Håkegård, Ulas Bagci
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Abstract

Artificial Intelligence (AI) is reshaping healthcare through advancements in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered tools are increasingly matching or exceeding specialist-level performance across multiple domains, paving the way for a new era of democratized healthcare access. These systems promise to reduce disparities in care delivery across demographic, racial, and socioeconomic boundaries by providing high-quality diagnostic support at scale. As a result, advanced healthcare services can be affordable to all populations, irrespective of demographics, race, or socioeconomic background. The democratization of such AI tools can reduce the cost of care, optimize resource allocation, and improve the quality of care. In contrast to humans, AI can potentially uncover complex relationships in the data from a large set of inputs and generate new evidence-based knowledge in medicine. However, integrating AI into healthcare raises several ethical and philosophical concerns, such as bias, transparency, autonomy, responsibility, and accountability. In this study, we examine recent advances in AI-enabled medical image analysis, current regulatory frameworks, and emerging best practices for clinical integration. We analyze both technical and ethical challenges inherent in deploying AI systems across healthcare institutions, with particular attention to data privacy, algorithmic fairness, and system transparency. Furthermore, we propose practical solutions to address key challenges, including data scarcity, racial bias in training datasets, limited model interpretability, and systematic algorithmic biases. Finally, we outline a conceptual algorithm for responsible AI implementations and identify promising future research and development directions.

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将人工智能伦理原则应用于医疗实践的概念框架
人工智能(AI)正在通过临床决策支持和诊断能力的进步重塑医疗保健。虽然人类的专业知识仍然是医疗实践的基础,但人工智能工具在多个领域的表现越来越接近或超过专家水平,为民主化医疗保健获取的新时代铺平了道路。这些系统有望通过大规模提供高质量的诊断支持,减少医疗服务在人口、种族和社会经济方面的差异。因此,无论人口统计学、种族或社会经济背景如何,所有人都可以负担得起先进的医疗保健服务。这种人工智能工具的民主化可以降低护理成本,优化资源配置,提高护理质量。与人类相比,人工智能可以从大量输入的数据中发现复杂的关系,并在医学领域产生新的循证知识。然而,将人工智能整合到医疗保健中会引发一些伦理和哲学问题,例如偏见、透明度、自主权、责任和问责制。在本研究中,我们研究了人工智能医学图像分析的最新进展、当前的监管框架以及临床整合的新兴最佳实践。我们分析了在医疗机构部署人工智能系统所固有的技术和道德挑战,特别关注数据隐私、算法公平性和系统透明度。此外,我们提出了解决关键挑战的实际解决方案,包括数据稀缺、训练数据集中的种族偏见、有限的模型可解释性和系统算法偏见。最后,我们概述了负责任的人工智能实施的概念算法,并确定了有希望的未来研究和发展方向。
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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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