Patellar Dislocation Patients Had Lower Bone Mineral Density and Hounsfield Unit Values in the Knee Joint Compared to Patients with Anterior Cruciate Ligament Ruptures: A Focus on Cortical Bone in the Tibia.

IF 3.7 3区 医学 Q2 ENGINEERING, BIOMEDICAL Bioengineering Pub Date : 2025-02-08 DOI:10.3390/bioengineering12020165
Yue Wu, Yiting Wang, Haijun Wang, Shaowei Jia, Yingfang Ao, Xi Gong, Zhenlong Liu
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Abstract

Anterior cruciate ligament (ACL) rupture and patellar dislocation (PD) are common knee injuries. Dual-energy X-ray absorptiometry (DXA) and computed tomography (CT) are widely used clinical diagnostic tools. The aim was to investigate the characteristics of knee bone mineral density (BMD) in patients with ACL rupture and PD and to explore the relationship between BMD and Hounsfield unit (HU) values. This prospective cross-sectional study included 32 ACL rupture and 32 PD patients assessed via DXA and CT. BMD and CT measurements were taken from regions of interest in the femoral and tibial condyles. Statistical analyses included t-tests and mixed-effects models. The results showed that BMD in the PD group was significantly lower than in the ACL group (p < 0.05). The HU values of cortical bone in the femur and tibia differed significantly between the ACL group and the PD group (p < 0.05). The BMD of the femur and tibia showed significant correlations with the HU values of cancellous bone and cortical bone (p < 0.05). The conclusion was that PD patients had lower BMD and HU values in the femur and tibia compared to patients with ACL ruptures, particularly in the cortical bone of the tibia, and there was a strong correlation between HU value and BMD.

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髌骨脱位患者与前交叉韧带断裂患者相比,膝关节骨密度和Hounsfield单位值较低:胫骨皮质骨的焦点。
前交叉韧带(ACL)断裂和髌骨脱位(PD)是常见的膝关节损伤。双能x线吸收仪(DXA)和计算机断层扫描(CT)是广泛使用的临床诊断工具。目的是探讨前交叉韧带破裂合并PD患者的膝关节骨密度(BMD)特征,并探讨骨密度与Hounsfield单位(HU)值的关系。这项前瞻性横断面研究包括32例ACL破裂和32例PD患者,通过DXA和CT进行评估。骨密度和CT测量从股骨和胫骨髁感兴趣的区域。统计分析包括t检验和混合效应模型。结果显示,PD组骨密度显著低于ACL组(p < 0.05)。ACL组与PD组股骨、胫骨皮质骨HU值差异有统计学意义(p < 0.05)。股骨和胫骨的骨密度与松质骨和皮质骨的HU值呈显著相关(p < 0.05)。结论:PD患者股骨和胫骨的BMD和HU值低于ACL骨折患者,尤其是胫骨皮质骨,HU值与BMD有很强的相关性。
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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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