Comparisons of Correlates of Viral Suppression Among Adults Living With HIV/AIDS in Tanzania: Analysis With and Without Including Survey Designs.

IF 1.1 Q4 INFECTIOUS DISEASES AIDS Research and Treatment Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI:10.1155/arat/3817430
Dayani Adam, Ramkumar T Balan
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Abstract

The effects of ignoring survey designs during the analysis of complex survey data may lead to biased estimates. This has been a common practice for most researchers. It is more critical for public health data which involve the clinical decisions that decide the fate of people's lives. This analysis compares the estimates of factors of viral load suppression (VLS) with and without including survey designs using the Tanzania HIV Impact Survey (THIS). This survey reveals factors associated with VLS among Tanzanians living with HIV/AIDS. The correlates of VLS were examined using multivariable logistic regression models in both cases with and without including survey design. The study unveils significant correlates such as age, middle wealth quintile, CD4, adherence, and antiretroviral (ARV) detection status of a patient. Furthermore, the study emphasizes the essence of properly accounting for CSD. Failure to do so may result in biased parameter estimates and incorrect variances; hence, incorrect inferences. Thus, the study's findings on VLS determinants have significant practical implications that allow government agencies and stakeholders to establish targeted and successful HIV/AIDS prevention and treatment initiatives. Consequently, this study suggests a complex design as an approach for obtaining unbiased estimates on the national representative surveys.

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在分析复杂的调查数据时,忽略调查设计的影响可能会导致估计结果出现偏差。这已成为大多数研究人员的惯常做法。对于涉及决定人们生命命运的临床决策的公共卫生数据来说,这一点更为重要。本分析利用坦桑尼亚艾滋病影响调查(THIS),比较了包含和不包含调查设计的病毒载量抑制(VLS)因素估计值。该调查揭示了坦桑尼亚艾滋病毒/艾滋病感染者中与病毒载量抑制相关的因素。使用多变量逻辑回归模型对包含和不包含调查设计的情况下 VLS 的相关因素进行了研究。研究揭示了一些重要的相关因素,如患者的年龄、中等财富五分位数、CD4、依从性和抗逆转录病毒(ARV)检测状况。此外,该研究还强调了适当考虑 CSD 的重要性。如果不这样做,可能会导致参数估计偏差和不正确的方差,从而得出不正确的推论。因此,本研究关于 VLS 决定因素的发现具有重要的现实意义,有助于政府机构和利益相关者制定有针对性的、成功的艾滋病毒/艾滋病预防和治疗措施。因此,本研究建议采用复杂设计作为获得全国代表性调查无偏见估计值的方法。
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来源期刊
AIDS Research and Treatment
AIDS Research and Treatment INFECTIOUS DISEASES-
CiteScore
3.10
自引率
0.00%
发文量
13
审稿时长
18 weeks
期刊介绍: AIDS Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focused on all aspects of HIV and AIDS, from the molecular basis of disease to translational and clinical research. In addition, articles relating to prevention, education, and behavior change will be considered
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