A dual-purpose electrode material for voltametric quantification of uric acid and supercapacitor performance using dysprosium-doped CaZrO3

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL Microchemical Journal Pub Date : 2025-04-01 Epub Date: 2025-02-24 DOI:10.1016/j.microc.2025.113081

Nandini Robin Nadar , J. Deepak , S.C. Sharma , B.R.Radha Krushna , Chitathoor Sridhar , Samir Sahu , R. Sudarmani , Chandrasekaran Krithika , S. Vijayanand , I.S. Pruthviraj , H. Nagabhushana

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Abstract

The development of advanced materials for biosensors has significantly enhanced the capability for efficient monitoring of uric acid, a critical biomarker for various diseases, including gout, cardiovascular disorders, and chronic kidney disease. This paper explores the novel application of dysprosium-doped calcium zirconate (DCZO) nanoparticles in electrochemical biosensors and supercapacitors for the first time. The DCZO-modified carbon paste electrode (MCPE) demonstrated a notable increase in sensitivity for uric acid (UA) detection, achieving a detection limit of 0.416 µM, with optimal performance at a pH of 7.0. The sensor exhibited linear responses to varying uric acid concentrations, scan rates, and dopamine (DA) interference, with R² values around 0.99. In supercapacitor applications, DCZO nanomaterials showed a remarkable specific capacitance of 224.8 F/g at a sweep rate of 2 mV/s, maintaining 86.36 % capacitance retention after 5000 cycles. These findings highlight the dual functionality of DCZO as an effective biosensor for uric acid detection and a robust material for supercapacitor applications.

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一种用于尿酸伏安定量和使用镝掺杂CaZrO3的超级电容器性能的双重用途电极材料

尿酸是痛风、心血管疾病和慢性肾脏疾病等多种疾病的重要生物标志物，而生物传感器先进材料的开发大大提高了对尿酸的有效监测能力。本文首次探讨了掺杂镝锆酸钙纳米颗粒在电化学生物传感器和超级电容器中的新应用。dczo修饰的碳糊电极（MCPE）对尿酸（UA）的检测灵敏度显著提高，检测限为0.416µM， pH为7.0时性能最佳。该传感器对不同尿酸浓度、扫描速率和多巴胺（DA）干扰表现出线性响应，R2值约为0.99。在超级电容器应用中，DCZO纳米材料在2 mV/s的扫描速率下表现出224.8 F/g的显着比电容，在5000次循环后保持86.36%的电容保留率。这些发现突出了DCZO作为尿酸检测的有效生物传感器和超级电容器应用的坚固材料的双重功能。

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来源期刊

Microchemical Journal 化学-分析化学

CiteScore

8.70

自引率

8.30%

发文量

1131

审稿时长

1.9 months

期刊介绍： The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field. Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.