Spherical Magnetic Fe-Alginate Microgels Fabricated by Droplet-Microfluidics Combining with an External Crosslinking Approach and the Study of Their pH Dependent Fe3+ Release Behaviors

IF 4.1 2区 化学 Q2 POLYMER SCIENCE Chinese Journal of Polymer Science Pub Date : 2024-12-05 DOI:10.1007/s10118-025-3257-2
Jie Chen, Run-Yu Yu, Kai-Qi Wang, Zhe-Yu Zhang, Arezoo Ardekani, Yuan-Du Hu
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Abstract

Due to the rapid development and potential applications of iron(III)-alginate (Fe-Alg) microgels in biomedical as well as environmental engineering, this study explores the preparation and characterization of spherical Fe-Alg microgels using droplet microfluidics combined with an external ionic crosslinking method. This study focused on the role of Fe3+ and examined its effects on the physical/chemical properties of microgels under different ionic conditions and reduced or oxidized states. The pH-dependent release behavior of Fe3+ from these microgels demonstrates their potential biomedical and environmental applications. Furthermore, the microgels can exhibit magnetism simply by utilizing in situ oxidation, which can be further used for targeted drug delivery and magnetic separation technologies.

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通过液滴-微流体技术结合外部交联方法制备的球形磁性海藻酸铁微凝胶及其随 pH 值变化的 Fe3+ 释放行为研究
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来源期刊
Chinese Journal of Polymer Science
Chinese Journal of Polymer Science 化学-高分子科学
CiteScore
7.10
自引率
11.60%
发文量
218
审稿时长
6.0 months
期刊介绍: Chinese Journal of Polymer Science (CJPS) is a monthly journal published in English and sponsored by the Chinese Chemical Society and the Institute of Chemistry, Chinese Academy of Sciences. CJPS is edited by a distinguished Editorial Board headed by Professor Qi-Feng Zhou and supported by an International Advisory Board in which many famous active polymer scientists all over the world are included. The journal was first published in 1983 under the title Polymer Communications and has the current name since 1985. CJPS is a peer-reviewed journal dedicated to the timely publication of original research ideas and results in the field of polymer science. The issues may carry regular papers, rapid communications and notes as well as feature articles. As a leading polymer journal in China published in English, CJPS reflects the new achievements obtained in various laboratories of China, CJPS also includes papers submitted by scientists of different countries and regions outside of China, reflecting the international nature of the journal.
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