Leifeng Wang, Yue Wu, Tingwei Gu, Jing Zhao, Binbin Li
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引用次数: 0
Abstract
Amino acids play a significant role in the study of life sciences, pharmaceutical R&D, bioengineering, and so on. Artificial amino acid-based drugs are important in advancing therapeutic innovation including chronic pain, diabetes, and Alzheimer's disease. Multicomponent reactions (MCRs) are demonstrated to be a powerful strategy for the construction of complicated structures from readily accessible starting reagents in one pot. Thus, applying multicomponent reactions to the preparation of amino acids and derivatives can be a potent strategy for advancing the research of pharmaceutical chemistry. With the rapid development of various catalytic methods and multicomponent reactions, this review outlines recent construction methods of amino acid derivatives by transition metal-catalyzed, light-mediated and other organocatalytic multicomponent reactions.
期刊介绍:
The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry:
Liebigs Annalen
Bulletin des Sociétés Chimiques Belges
Bulletin de la Société Chimique de France
Gazzetta Chimica Italiana
Recueil des Travaux Chimiques des Pays-Bas
Anales de Química
Chimika Chronika
Revista Portuguesa de Química
ACH—Models in Chemistry
Polish Journal of Chemistry.