Shanshan Wang , Xiaoni Wang , Yuxin Zhao, Lin Xie, Jianbao Zhang
{"title":"A feedback loop study of brain-heart interaction based on HEP and HRV","authors":"Shanshan Wang , Xiaoni Wang , Yuxin Zhao, Lin Xie, Jianbao Zhang","doi":"10.1016/j.bbe.2025.02.005","DOIUrl":null,"url":null,"abstract":"<div><div>Although growing evidences suggest heartbeat evoked potential (HEP) as a biomarker of interoception, little is known about how HEP is related to cardiovascular function. In the article, mental arithmetic and meditation tasks that respectively activate sympathetic and parasympathetic activities were designed, and electroencephalogram and cardiovascular parameters were recorded in healthy young males. Our findings revealed a decrease in HEP during mental arithmetic and an increase during meditation. A correlation between HEP and blood pressure was also observed, indicating that baroreceptor stretch may contribute to HEP generation. Furthermore, HEP showed a positive correlation with parasympathetic activity and a negative correlation with sympathetic activity. Collectively, these results suggest the presence of a potential negative feedback loop between the brain and heart, mediated by HEP.</div></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"45 2","pages":"Pages 181-188"},"PeriodicalIF":5.3000,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biocybernetics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0208521625000105","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Although growing evidences suggest heartbeat evoked potential (HEP) as a biomarker of interoception, little is known about how HEP is related to cardiovascular function. In the article, mental arithmetic and meditation tasks that respectively activate sympathetic and parasympathetic activities were designed, and electroencephalogram and cardiovascular parameters were recorded in healthy young males. Our findings revealed a decrease in HEP during mental arithmetic and an increase during meditation. A correlation between HEP and blood pressure was also observed, indicating that baroreceptor stretch may contribute to HEP generation. Furthermore, HEP showed a positive correlation with parasympathetic activity and a negative correlation with sympathetic activity. Collectively, these results suggest the presence of a potential negative feedback loop between the brain and heart, mediated by HEP.
期刊介绍：
Biocybernetics and Biomedical Engineering is a quarterly journal, founded in 1981, devoted to publishing the results of original, innovative and creative research investigations in the field of Biocybernetics and biomedical engineering, which bridges mathematical, physical, chemical and engineering methods and technology to analyse physiological processes in living organisms as well as to develop methods, devices and systems used in biology and medicine, mainly in medical diagnosis, monitoring systems and therapy. The Journal''s mission is to advance scientific discovery into new or improved standards of care, and promotion a wide-ranging exchange between science and its application to humans.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
