Disfunción endotelial y anomalías vasculares en acromegalia. A propósito de un caso

IF 0.7 4区医学 Q4 NEUROSCIENCES Neurocirugia Pub Date : 2025-03-01 DOI:10.1016/j.neucir.2024.09.006

Ana Irigaray Echarri , M. Dolores Ollero García-Agulló , José Jorge Ortez Toro , Idoya Zazpe Cenoz

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Abstract

In patients with acromegaly, the pleiotropic effects of GH and IGF-1 have been associated with the development of endothelial dysfunction and vascular abnormalities.

We present the case of a 45-year-old male diagnosed with acromegaly. Magnetic resonance imaging identified a marked dilatation and medialization of both cavernous internal carotid arteries (ICA), leading to a narrow intercarotid distance, a phenomenon known as “carotid kisses”.

This vascular alteration has been described in greater proportion in patients with acromegaly. The anomalies that are also present with greater prevalence in these patients are: aneurysms of the ICA, protrusion of the ICA into the sphenoid sinus, narrow intercarotid distance, fusiform dilatation of the ICA and dehiscence of this artery in the bony canal. The presence of such alterations increases the risk of injury to the ICA.

Pre-surgical detection of such abnormalities is essential to ensure the safety of the surgical approach.

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来源期刊

Neurocirugia 医学-神经科学

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

60 days

期刊介绍： Neurocirugía is the official Journal of the Spanish Society of Neurosurgery (SENEC). It is published every 2 months (6 issues per year). Neurocirugía will consider for publication, original clinical and experimental scientific works associated with neurosurgery and other related neurological sciences. All manuscripts are submitted for review by experts in the field (peer review) and are carried out anonymously (double blind). The Journal accepts works written in Spanish or English.