Cholera invasion speed and the intervention strength

IF 1.2 3区 数学 Q1 MATHEMATICS Journal of Mathematical Analysis and Applications Pub Date : 2025-08-15 Epub Date: 2025-02-25 DOI:10.1016/j.jmaa.2025.129411
Komi Afassinou , Ousmane Koutou , Narcisse Roland Loufouma Makala
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Abstract

We formulate a mathematical model which captures the essential dynamics of cholera infection transmission. Control interventions such as vaccination program and environmental sanitation service are incorporated to analyse the impact of both interventions on the infection dynamics. The qualitative and numerical analyses of the model are carried out. Through these analyses, a great attention is brought to certain uncommonly used infection features such as invasion speed of an infection which historically has been ignored by infectious disease modellers. The analyses of these key model parameters not only reveal the required intervention strength needed to curb the infection spread but also indicate which either control intervention should be prioritised. The numerical results approve the qualitative findings and promise an infection free population, should the control intervention speed be greater than the invasion speed of the infection.
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霍乱入侵速度与干预力度
我们制定了一个数学模型,捕捉霍乱感染传播的基本动态。将疫苗接种规划和环境卫生服务等控制干预措施纳入分析这两种干预措施对感染动态的影响。对模型进行了定性和数值分析。通过这些分析,极大地关注了一些不常用的感染特征,如感染的入侵速度,这些特征在历史上一直被传染病建模者所忽视。对这些关键模型参数的分析不仅揭示了遏制感染传播所需的干预力度,而且还指出了应优先采取哪一种控制干预措施。数值结果与定性结果一致,当控制干预速度大于感染入侵速度时,有望形成无感染群体。
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来源期刊
CiteScore
2.50
自引率
7.70%
发文量
790
审稿时长
6 months
期刊介绍: The Journal of Mathematical Analysis and Applications presents papers that treat mathematical analysis and its numerous applications. The journal emphasizes articles devoted to the mathematical treatment of questions arising in physics, chemistry, biology, and engineering, particularly those that stress analytical aspects and novel problems and their solutions. Papers are sought which employ one or more of the following areas of classical analysis: • Analytic number theory • Functional analysis and operator theory • Real and harmonic analysis • Complex analysis • Numerical analysis • Applied mathematics • Partial differential equations • Dynamical systems • Control and Optimization • Probability • Mathematical biology • Combinatorics • Mathematical physics.
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