Does Robotic-Assisted Total Knee Arthroplasty Improve Outcomes of Adult Osteoarthritis Patients-A Systematic Review and Trial Sequential Meta-Analysis.
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引用次数: 0
Abstract
Background and objectives: Total knee arthroplasty (TKA) is a standard treatment for end-stage knee osteoarthritis (KOA). While conventional TKA (cTKA) is widely used, robotic-assisted TKA (rTKA) has gained attention for its potential precision and improved outcomes. However, the comparative efficacy and safety of rTKA versus cTKA remain unclear due to inconsistent findings in existing studies. This study aims to systematically review and compare the efficacy and safety of rTKA and cTKA in patients with KOA.
Methods: A total of seven databases were searched. Only randomized controlled trials (RCTs) were included in this systematic review. Subgroup analysis, sensitivity analysis, and trial sequential analysis (TSA) were used to evaluate the stability of the results.
Results: Twenty-five RCTs involving 3156 patients with KOA were included. The only statistically significant clinical difference between patients who received rTKA and cTKA was that the rTKA group was associated with a longer operative duration (MD = 22.38 mins; 95% confidence interval [CI] [12.86, 31.91]; p < 0.00001; I 2 = 98%). As for functional parameters, the two groups had similar results in postoperative Knee Society Score (KSS), the Western Ontario and McMaster Universities (WOMAC), and Hospital for Special Surgery Score (HSS). Regarding the tibiofemoral angle and the coronal femoral component angle, no significant difference was observed between the two groups. Patients in the rTKA group had a higher hip-knee-ankle angle (HKA) (MD = 0.63; 95% CI [0.23, 1.03]; p = 0.002; I 2 = 52%), lower HKA deviation (MD = -0.99; 95% CI [-1.24, -0.74]; p < 0.00001; I 2 = 0%), and a higher coronal tibial component angle (MD = 0.46; 95% CI [0.07, 0.85]; p = 0.02; I 2 = 81%) after the surgery.
Conclusions: While rTKA appears to be a feasible and safe alternative to cTKA, the mixed evidence from our study highlights the need for further research to fully understand its clinical implications and long-term outcomes.
机器人辅助全膝关节置换术能否改善成人骨关节炎患者的疗效--系统回顾与试验序列荟萃分析》（Robotic-Assisted Total Knee Arthropasty Does Improve Outcomes of Adult Osteoarthritis Patients-A Systematic Review and Trial Sequential Meta-Analysis）。
期刊介绍：
Orthopaedic Surgery (OS) is the official journal of the Chinese Orthopaedic Association, focusing on all aspects of orthopaedic technique and surgery.
The journal publishes peer-reviewed articles in the following categories: Original Articles, Clinical Articles, Review Articles, Guidelines, Editorials, Commentaries, Surgical Techniques, Case Reports and Meeting Reports.
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