National investment case development for pathogen genomics.

IF 11.1 Q1 CELL BIOLOGY Cell genomics Pub Date : 2025-03-12 Epub Date: 2025-02-27 DOI:10.1016/j.xgen.2025.100781
Yoong Khean Khoo, Suci Wulandari, Marya Getchell, La Moe, Shurendar Selva Kumar, Elyssa Jiawen Liu, Yimei Sun, Junxiong Pang, Swapnil Mishra, Hannah Clapham, Ben Marais, Vitali Sintchenko, Ruklanthi de Alwis, David Hipgrave, Paul Michael Pronyk
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Abstract

Sustaining and expanding genomic surveillance capacity requires broader investment in genomics that target both novel and pandemic pathogens. Currently, there is no standardized methodology to evaluate the cost and benefit of a multi-pathogen surveillance system. We propose a framework for pathogen genomic surveillance that links public health and systems considerations to a stepwise approach.

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病原体基因组学国家投资案例开发。
维持和扩大基因组监测能力需要对针对新型和大流行病原体的基因组学进行更广泛的投资。目前,还没有标准化的方法来评估多病原体监测系统的成本和效益。我们提出了病原体基因组监测框架,将公共卫生和系统考虑与逐步方法联系起来。
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