BPA and its analogues in thermal papers: an assessment of presence and dermal exposure†

IF 3.5 Q3 ENGINEERING, ENVIRONMENTAL Environmental science. Advances Pub Date : 2025-01-03 DOI:10.1039/D4VA00132J
Merve Ozkaleli Akcetin, Hatice Kubra Gul, Ismail Ethem Goren, Nebile Daglioglu and Perihan Binnur Kurt-Karakus
{"title":"BPA and its analogues in thermal papers: an assessment of presence and dermal exposure†","authors":"Merve Ozkaleli Akcetin, Hatice Kubra Gul, Ismail Ethem Goren, Nebile Daglioglu and Perihan Binnur Kurt-Karakus","doi":"10.1039/D4VA00132J","DOIUrl":null,"url":null,"abstract":"<p >Thermal papers are a significant source of exposure to bisphenol A (BPA) and other phenolic compounds (PCs), absorbed through the skin <em>via</em> dermal contact. This study analyzed thermal paper receipts from various commercial settings in Türkiye to assess BPA and its structural analogs. For both deterministic and probabilistic risk assessments, the estimated daily intake (EDI), hazard quotient (HQ), and hazard index (HI) were calculated for the general population and workers exposed <em>via</em> dermal contact from handling thermal receipts. The results showed that BPA and bisphenol S (BPS) were the most frequently detected chemicals (detected in 99% and 100% of samples, respectively) with concentrations ranging from 1.98–1061 μg per g paper and 0.070–210 μg per g paper in thermal paper receipts in Türkiye, respectively. The EDI of PCs based on the mean concentration determined in the samples for the general population ranged between 0.00000184 μg per kg per day and 0.000445 μg per kg per day, whereas it ranged between 0.0000919 μg per kg per day and 0.022 μg per kg per day for occupational exposure of workers. The EDI value based on the mean concentration detected in samples was 0.000445 μg per kg per day and 0.00223 μg per kg per day for the general population and occupational exposure, respectively. Exposure to BPS was lower, resulting in exposure values of 0.000039 μg per kg per day and 0.002 μg per kg per day for the general population and occupational exposure, respectively. Although these mean concentration based exposure levels are below the U.S. EPA reference dose (50 μg per kg per day for BPA), they exceed the more stringent European Food Safety Authority (EFSA) total daily intake (TDI) limits set for BPA (0.0002 μg per kg per day) in some cases, indicating potential health risks. The HQ and HI analyses further underscore the risks, particularly for workers, with HI values surpassing safe thresholds. The study calls for stricter regulations on BPA and its analogs in thermal papers due to the significant risks, even from BPA-free products that use BPS as a substitute.</p>","PeriodicalId":72941,"journal":{"name":"Environmental science. Advances","volume":" 3","pages":" 489-502"},"PeriodicalIF":3.5000,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/va/d4va00132j?page=search","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental science. Advances","FirstCategoryId":"1085","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2025/va/d4va00132j","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, ENVIRONMENTAL","Score":null,"Total":0}
引用次数: 0

Abstract

Thermal papers are a significant source of exposure to bisphenol A (BPA) and other phenolic compounds (PCs), absorbed through the skin via dermal contact. This study analyzed thermal paper receipts from various commercial settings in Türkiye to assess BPA and its structural analogs. For both deterministic and probabilistic risk assessments, the estimated daily intake (EDI), hazard quotient (HQ), and hazard index (HI) were calculated for the general population and workers exposed via dermal contact from handling thermal receipts. The results showed that BPA and bisphenol S (BPS) were the most frequently detected chemicals (detected in 99% and 100% of samples, respectively) with concentrations ranging from 1.98–1061 μg per g paper and 0.070–210 μg per g paper in thermal paper receipts in Türkiye, respectively. The EDI of PCs based on the mean concentration determined in the samples for the general population ranged between 0.00000184 μg per kg per day and 0.000445 μg per kg per day, whereas it ranged between 0.0000919 μg per kg per day and 0.022 μg per kg per day for occupational exposure of workers. The EDI value based on the mean concentration detected in samples was 0.000445 μg per kg per day and 0.00223 μg per kg per day for the general population and occupational exposure, respectively. Exposure to BPS was lower, resulting in exposure values of 0.000039 μg per kg per day and 0.002 μg per kg per day for the general population and occupational exposure, respectively. Although these mean concentration based exposure levels are below the U.S. EPA reference dose (50 μg per kg per day for BPA), they exceed the more stringent European Food Safety Authority (EFSA) total daily intake (TDI) limits set for BPA (0.0002 μg per kg per day) in some cases, indicating potential health risks. The HQ and HI analyses further underscore the risks, particularly for workers, with HI values surpassing safe thresholds. The study calls for stricter regulations on BPA and its analogs in thermal papers due to the significant risks, even from BPA-free products that use BPS as a substitute.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
1.90
自引率
0.00%
发文量
0
期刊最新文献
Back cover Back cover Effect of seawater acidification on energy metabolism in the hydrocoral Millepora alcicornis: inhibition of citrate synthase activity indicates disruption in aerobic pathways† eDNA metabarcoding-based source attribution of fecal indicator bacteria exceedances in urban freshwater beaches, sand and rivers† Local sources versus long-range transport of organic contaminants in the Arctic: future developments related to climate change†
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1