Ten-year-long implementation of a bundle for the prevention of surgical site infections: A cohort study of the temporal trend and factors influencing compliance

IF 2.4 3区 医学 Q2 INFECTIOUS DISEASES American journal of infection control Pub Date : 2025-06-01 Epub Date: 2025-02-28 DOI:10.1016/j.ajic.2025.02.013
Federico Cussotto MD, Costanza Vicentini MD, Luca Bresciano MD, Marta Castagnotto MD, Tommaso Cocchi MD, Dayana Indira Herr Ferrer MD, Carla Maria Zotti PhD, on behalf of the Working Group “Unità Prevenzione Rischio Infettivo (UPRI), Regione Piemonte”
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Abstract

Background

Many bundles have proven effective at preventing surgical site infections (SSIs), but little is known about factors influencing compliance to such bundles.

Methods

This cohort study includes 41,400 surgeries performed in 47 hospitals throughout a decade. The outcome of interest was binary compliance with a 4-element bundle for SSI prevention. A multivariable logistic regression model was computed with 12 predictor variables: patient sex, age, American Society of Anesthesiologists score, surgical specialty, length of preoperative stay, procedure year, procedure duration, surgical technique, presence of a prosthetic implant, elective versus emergent procedure, hospital type, and hospital size.

Results

Bundle compliance has increased significantly since its implementation, reaching 67.1% in the latest year. Lower odds of bundle compliance are correlated with emergent procedures (OR 0.3697), procedure duration above the first tertile (0.8597), age above the first quartile (0.7365), absence of a prosthetic implant, open surgical technique, and preoperative stay above 1 day (0.7920).

Discussion

Older age, longer procedure duration, longer preoperative stay, and an open surgical technique all correlate negatively with bundle compliance and are also known risk factors for SSIs.

Conclusions

Certain patient subgroups are at higher risk for bundle noncompliance, and thus show greater margins for improvement.
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手术部位感染预防捆绑治疗的十年实施:时间趋势和影响依从性因素的队列研究。
背景:许多药物束已被证明在预防手术部位感染(ssi)方面是有效的,但对影响这些药物束依从性的因素知之甚少。方法:本队列研究包括47家医院近十年来进行的41400例手术。感兴趣的结果是对预防SSI的4元素束的二元依从性。采用多变量logistic回归模型计算12个预测变量:患者性别、年龄、ASA评分、手术专科、术前住院时间、手术年份、手术持续时间、手术技术、是否植入假体、选择性手术与紧急手术、医院类型和医院规模。结果:Bundle实施以来,合规率显著提高,最近一年达到67.1%。较低的束依从率与紧急手术相关(OR 0.3697),手术时间超过第一个四分位数(0.8597),年龄超过第一个四分位数(0.7365),没有植入假体,开放式手术技术,术前停留时间超过1天(0.7920)。讨论:年龄较大,手术时间较长,术前停留时间较长,开放性手术技术都与束依从性负相关,也是ssi的已知危险因素。结论:某些患者亚组有较高的束不依从性风险,因此有较大的改善余地。
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来源期刊
CiteScore
7.40
自引率
4.10%
发文量
479
审稿时长
24 days
期刊介绍: AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)
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