Renal Osteodystrophy in 2 Canine Patients.

Abstract

This report presents 2 cases of renal osteodystrophy in young to middle-aged dogs, emphasizing the clinical presentation, diagnostic challenges, and therapeutic management. Both cases exhibited similar symptoms including oral abnormalities and renal dysfunction, with radiographic evidence revealing substantial bone resorption in the mandibles and maxillae. Histological analysis post-mortem confirmed advanced chronic kidney disease characterized by extensive fibrosis and glomerular abnormalities. The report underscores the critical importance of early detection of chronic kidney disease to mitigate the development of secondary hyperparathyroidism and subsequent renal osteodystrophy. These cases illustrate the complexities of diagnosing and managing renal osteodystrophy in dogs, highlighting the need for comprehensive diagnostic approaches combining clinical evaluation, radiographic imaging, and histopathological examination. Effective management strategies discussed include dietary modification, phosphate binding agents, and supportive care to alleviate clinical symptoms and slow progression of disease. The outcomes underscore the grave prognosis associated with advanced stages of chronic kidney disease and emphasize the significance of proactive screening and early intervention in mitigating renal osteodystrophy in canine patients.