A communication pipeline for in vivo imaging core facilities.

Abstract

During the last years, the rapidly evolving imaging technologies have become valuable tools in in vivo research. Imaging modalities provide high resolution, real-time images and videos, offering the opportunity of longitudinal, quantitative, non-invasive/non-terminal monitoring of animal models. In parallel, in vivo imaging applications lead to animal reduction, by substituting phenotyping methods that require euthanasia. For in vivo imaging core facilities, effective communication is an essential tool that ensures that all teams involved are on the same page at all times. Successful communication is necessary at all stages and may be achieved via standardized procedures, which provide specifications and step-by-step instructions for all operations and activities. This article aims to provide a communication pipeline for imaging facilities operating with a full-service model, developed for 'Alexander Fleming' Animal Facilities, helping to achieve smooth operation and high-quality research.