L Morichon, S Assou, A Bourdin, D Muriaux, J De Vos
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引用次数: 0
Abstract
Highlighted by the COVID-19 pandemic, the study of respiratory infections is a global health priority. To this end, many preclinical in vitro study models have been developed to reproduce nasal, bronchial or alveolar respiratory epithelium. These models can be established from immortalised cell lines, primary culture or induced pluripotent stem cells (iPSC). They can also be constructed in various three-dimensional structures that are more or less physiological and easy to use. This synthetic review puts into perspective the advantages and limitations of these models, while highlighting their relevance for the study of the mechanisms of SARS-CoV-2 infection.
期刊介绍：
La Revue des Maladies Respiratoires est l''organe officiel d''expression scientifique de la Société de Pneumologie de Langue Française (SPLF). Il s''agit d''un média professionnel francophone, à vocation internationale et accessible ici.
La Revue des Maladies Respiratoires est un outil de formation professionnelle post-universitaire pour l''ensemble de la communauté pneumologique francophone. Elle publie sur son site différentes variétés d''articles scientifiques concernant la Pneumologie :
- Editoriaux,
- Articles originaux,
- Revues générales,
- Articles de synthèses,
- Recommandations d''experts et textes de consensus,
- Séries thématiques,
- Cas cliniques,
- Articles « images et diagnostics »,
- Fiches techniques,
- Lettres à la rédaction.
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