Nanocellulose Extraction from Biomass Waste: Unlocking Sustainable Pathways for Biomedical Applications.

IF 7 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Chemical record Pub Date : 2025-03-04 DOI:10.1002/tcr.202400249

Mehrdad Ghamari, Suvish, Chan Hwang See, Hongnian Yu, Thiyagarajan Anitha, V T Balamurugan, Sasireka Velusamy, David Hughes, Senthilarasu Sundaram

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Abstract

The escalating global waste crisis necessitates innovative solutions. This study investigates the sustainable production of nanocellulose from biomass waste and its biomedical applications. Cellulose-rich materials-including wood, textiles, agricultural residues, and food by-products-were systematically processed using alkaline, acid, and oxidative pretreatments to enhance fiber accessibility. Mechanical techniques, such as grinding and homogenization, combined with chemical methods like acid hydrolysis and 2,2,6,6-Tetramethylpiperidin-1-yl-oxyl (TEMPO) oxidation, were employed to successfully isolate nanocellulose. Post-treatment modifications, including surface coating and cross-linking, further tailored its properties for specific applications. The results demonstrated nanocellulose's biocompatibility, biodegradability, and functional versatility. In wound healing, it enhanced moisture management and exhibited antimicrobial properties. Its high surface area facilitated efficient drug loading and controlled release in drug delivery applications. Nanocellulose bioinks supported cell proliferation in 3D bioprinting for tissue engineering. Additional applications in biosensors and personal care products were also identified. This study advances sustainable materials science, aligning resource conservation with circular economy principles to address biomedical sector needs.

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来源期刊

Chemical record 化学-化学综合

CiteScore

11.00

自引率

3.00%

发文量

188

审稿时长

>12 weeks

期刊介绍： The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.